Results 1 to 10 of about 190,021 (386)

Loganin Exerts Sedative and Hypnotic Effects via Modulation of the Serotonergic System and GABAergic Neurons

open access: yesFrontiers in Pharmacology, 2019
Corni fructus, the fruit of Cornus officinalis Sieb. et Zucc., has been used as a tonic for the kidney in China for thousands of years. Loganin is one of the major constituents derived from Corni fructus.
Rui Shi   +12 more
doaj   +2 more sources

Dexmedetomidine vs Fentanyl for Awake Fiberoptic Intubation in Paediatric Patients with Temporomandibular Joint Ankylosis: A Retrospective Analysis [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Introduction: For successful management of difficult paediatric airway intubation, proper preparation of airway along with a calm and sedated child with titrated doses of sedative agents is paramount. Aim: To compare two different classes of sedative
Reena Mahajan   +5 more
doaj   +1 more source

Citrus limon (L.) Burm f. Essential Oil Has Anxiolytic and Sedative Properties by Modulating GABAA-Receptors [PDF]

open access: yesBrazilian Archives of Biology and Technology, 2020
The high prevalence of anxiety disorders associated with pharmacotherapy side effects have motivated the search for new pharmacological agents. Species from Citrus genus, such as Citrus limon (sicilian lemon), have been used in folk medicine as a ...
Max Denisson Mauricio Viana   +7 more
doaj   +1 more source

Effect of Stress Ulcers Prophylaxis, Sedative and Statin on Ventilator-Associated Pneumonia: A Retrospective Analysis Based on MIMIC Database

open access: yesFrontiers in Pharmacology, 2022
Background: The use of MV can easily lead to VAP especially in ICU patients. SUP, sedatives, statin and insulin have been proved to prevent VAP and improve the prognosis of patients.
Xuetao Kong   +5 more
doaj   +1 more source

Remimazolam: An Updated Review of a New Sedative and Anaesthetic

open access: yesDrug Design, Development and Therapy, 2022
Remimazolam (CNS7056) is a novel benzodiazepine for intravenous sedation; it has an ultra-short duration of action and was recently approved for use in procedural sedation and general anaesthesia.
Qinxue Hu   +4 more
semanticscholar   +1 more source

Remimazolam: Non-Clinical and Clinical Profile of a New Sedative/Anesthetic Agent

open access: yesFrontiers in Pharmacology, 2021
A program to identify novel intravenous sedatives with a short and predictable duration of action was initiated in the late 1990’s by Glaxo Wellcome. The program focussed on the identification of ester-based benzodiazepine derivatives that are rapidly ...
Gavin Kilpatrick
semanticscholar   +1 more source

Can sedation be used for equine lameness investigation?

open access: yesVeterinary Evidence, 2021
PICO question In horses undergoing lameness investigation, does sedation with a2-adrenergic agonists alone versus sedation with a2-adrenergic agonists in combination with butorphanol tartrate effect the degree of lameness?
Helene Termansen, Lucinda Meehan
doaj   +1 more source

Phytomelatonin content in Valeriana officinalis L. and some related phytotherapeutic supplements

open access: yesInternational Journal of Plant Based Pharmaceuticals, 2022
The use of medicinal plants as an alternative phytotherapeutic remedy against mild illnesses and dysfunctions is increasingly embraced by people. Among these dysfunctions, episodes of nervousness and anxiety due to lack of sleep and insomnia are becoming
Marta Losada   +3 more
doaj   +1 more source

Efficacy and safety of sedation with dexmedetomidine in adults undergoing gastrointestinal endoscopic procedures: systematic review and meta-analysis of randomized controlled trials

open access: yesFrontiers in Pharmacology, 2023
Background: The sedative role of dexmedetomidine (DEX) in gastrointestinal endoscopic procedures is unclear. We performed this systematic review and meta-analysis to assess the efficacy and safety of sedation with DEX during gastrointestinal endoscopic ...
Rou Tang   +10 more
doaj   +1 more source

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models

open access: yesDrugs & Aging, 2021
Patients taking medication with high anticholinergic and sedative properties are at increased risk of experiencing poor cognitive and physical outcomes. Therefore, precise quantification of the cumulative burden of their drug regimen is advisable.
Sweilem B Al Rihani   +7 more
semanticscholar   +1 more source

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