Results 31 to 40 of about 195,235 (340)

Structure-Dependent Activity of Natural GABA(A) Receptor Modulators

Molecules, 2018
GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains.
Serhat Sezai Çiçek
doaj   +1 more source

Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]

, 2017
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi, Ami G. Shah, Anderson, Arlt, Barr, Barthelemy, Beiderlinden, Bein, Bembea, Bhatt-Meht, Boucher, Brandi N. Thoma, Brown, Buck, Buscher, Chung, Dagan, Dagan, de Montmollin, De Rosa, DeGrado, Donadello, Donadello, Dzierba, Erstad, Esper, Eyler, Flordelis Lasierra, Glauber, Greenberg, Gélisse, Hadidi, Hertzog, Hraiech, Hynynen, Johnston, Kawada, Kim, Koster, Krueger, Lamarche, Latronico, Lemaitre, Levison, Malfertheiner, Mehta, Michelle Peahota, Moore, Mousavi, Mulla, Mulla, Muntean, Oliver, Paden, Park, Perkins, Peters, Pettignano, Phillips, Pieri, Potter, Preston, Protti, Ranucci, Riker, Roberts, Roos, Rosen, Ruiz, Rybak, Saini, Sanfilippo, Satyapriya, Schmith, Shekar, Shekar, Shekar, Shekar, Shekar, Sherwin, Sklar, Smith, Spriet, Staudacher, Strunk, Subramaniam, Szefner, Tellor, Trudzinski, Tulman, Turner, Veinstein, Vilay, Wagner, Walter K. Kraft, Welsch, Wen, Wildschut, Wu, Young   +99 more
core   +2 more sources

The concept of ’Musa-pelo and the medicinal use of shrubby legumes (Fabaceae) in Lesotho

Bothalia: African Biodiversity & Conservation, 2007
In the Kingdom of Lesotho, 20 plant species are commonly known as  'Musa-pelo. The term literally means ‘the one who brings back or tums around the heart’.
A. Moteetee, B-E. van Wyk
doaj   +1 more source

Traditional Herbal Remedies Used for Managing Anxiety and Insomnia in Italy: An Ethnopharmacological Overview

Horticulturae, 2021
Anxiety and insomnia are among the most common mental health disorders and are a major cause of disability around the world. Traditional herbal medicines are receiving significant attention in global health debates. Several Italian regions maintain rural
Riccardo Motti, Bruna de Falco
doaj   +1 more source

Evaluation and Management of Sleep Disorders in the Hand Surgery Patient. [PDF]

, 2016
Despite posing a significant public health threat, sleep disorders remain poorly understood and often underdiagnosed and mismanaged. Although sleep disorders are seemingly unrelated, hand surgeons should be mindful of these because numerous conditions of
Gaspar, Michael P., Gaspar, Patrick S., Jacoby, Sidney M., Kane, Patrick M., Osterman, A. Lee   +4 more
core   +2 more sources

Neuropharmacological effects of the aqueous leaf extract and fractions of Pavetta crassipes (K. Schum) Rubiaceae in mice [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2017
Context: In Northern Nigeria, Pavetta crassipes (K. Schum) Rubiaceae leaf extracts are used in the treatment of convulsion, pain and mental illness; however, there is paucity of information on its neuropharmacological effects.
Moses W. Bariweni, Raymond I. Ozolua
doaj  

Comparing the Effect of Dexmedetomidine and Midazolam in Patients with Brain Injury

Brain Sciences, 2022
Background: Studies have shown that dexmedetomidine improves neurological function. Whether dexmedetomidine reduces mortality or improves quantitative electroencephalography (qEEG) among patients post-craniotomy remains unclear.
Yanxia Huang, Yunxin Deng, Renjing Zhang, Mei Meng, Dechang Chen   +4 more
doaj   +1 more source

Reducing the anticholinergic and sedative load in older patients on polypharmacy by pharmacist-led medication review: a randomised controlled trial

BMJ Open, 2018
Objective To evaluate if a pharmacist-led medication review is effective at reducing the anticholinergic/sedative load, as measured by the Drug Burden Index (DBI). Design Randomised controlled single blind trial.
Helene G. van der Meer, H. Wouters, Lisa G. Pont, K. Taxis   +3 more
semanticscholar   +1 more source

Experimental pharmacological research regarding the antidepressant effect of associating doxepin and selegiline in normal mice [PDF]

, 2019
The severity and complexity of depression can vary widely among individuals, thus making single drug therapy ineffective in some cases. Taking this fact into account and using a mouse model, we set on investigating the possibility of obtaining a ...
Chiriță, Cornel, Dănciulescu Miulescu, Rucsandra E, Limban, Carmen, Marineci, Cristina D, Mireșan, Horațiu, Negreș, Simona, Nuță, Diana C, Zbârcea, Cristina E, Ștefănescu, Emil   +8 more
core   +2 more sources

Sedative and anxiolytic effects of Capparis sicula Duhamel: in vivo and in silico approaches with phytochemical profiling

Frontiers in Pharmacology
The World Health Organization reports that 30% of adults worldwide suffer from insomnia, while 10% of people worldwide suffer with various forms of anxiety.
Büşra Karpuz Ağören, Esra Küpeli Akkol, Ismail Çelik, Eduardo Sobarzo-Sánchez, Eduardo Sobarzo-Sánchez   +4 more
doaj   +1 more source