Objective We aimed to assess differences in baseline characteristics, efficacy, and safety of advanced therapies between male and female patients with axial spondyloarthritis (axSpA) in randomized controlled trials (RCTs). Methods We conducted a systematic literature search for RCTs assessing the efficacy of advanced therapies in patients with axSpA ...
Angel Gao+5 more
wiley +1 more source
Sedation for Gastrointestinal Endoscopic Procedures in the Elderly: Getting Safer but Still Not Nearly Safe Enough [PDF]
Previously published UK reports showed that excessively large doses of benzodiazepines and opiates were being commonly used to sedate elderly patients for gastrointestinal (GI) endoscopy. This unsafe practice has lead to avoidable morbidity and mortality.
Bell, G. D.+8 more
core
Patient-maintained sedation for oral surgery using a target-controlled infusion of propofol - a pilot study [PDF]
OBJECTIVE: To assess the safety and efficacy of a new patient-maintained propofol system for conscious sedation in dentistry. DESIGN: Prospective clinical trial SETTING: Department of Sedation, Glasgow Dental Hospital and School, 2001 SUBJECTS AND ...
AW Murray+15 more
core +1 more source
Objective Walk With Ease (WWE) is a six‐week arthritis‐appropriate evidence‐based physical activity program traditionally offered in a face‐to‐face format. Because many populations encounter participation barriers to in‐person programs, WWE was modified for telephone delivery (WWE‐T).
Christine A. Pellegrini+5 more
wiley +1 more source
Safety and efficacy of a propofol and ketamine based procedural sedation protocol in children with cerebral palsy undergoing botulinum toxin A injections. [PDF]
Background Pediatric patients with cerebral palsy (CP) often undergo intramuscular botulinum toxin (BoNT‐A) injections. These injections can be painful and may require procedural sedation.
Abu-Sultaneh, Samer+4 more
core +1 more source
Objective Pediatric rheumatologic diseases (PRDs) are characterized by high rates of anxiety and depression known to impact health‐related outcomes. We present guidance statements to assess and manage mental health concerns for youth with PRDs in pediatric rheumatology practice.
Natoshia R. Cunningham+21 more
wiley +1 more source
Experimental pharmacological research regarding the antidepressant effect of associating doxepin and selegiline in normal mice [PDF]
The severity and complexity of depression can vary widely among individuals, thus making single drug therapy ineffective in some cases. Taking this fact into account and using a mouse model, we set on investigating the possibility of obtaining a ...
Chiriță, Cornel+8 more
core +1 more source
Effects of Chlordiazepoxide on Predator Odor-Induced Reductions of Playfulness in Juvenile Rats
The extent to which a non-sedative dose of chlordiazepoxide (CDP) is able to modify the behavioral responses toward a predator odor was assessed in juvenile rats.
DeBrouse, Lauren M.+2 more
core +1 more source
Diverse Treatment Goals in Psoriatic Arthritis: Insights From Participants in the PARC Cohort
Objective The aim of this study was to examine patient‐reported treatment goals among individuals with psoriatic arthritis. Methods Participants in the Psoriatic Arthritis Research Consortium completed standardized assessments, including patient‐reported outcome (PROs) instruments, between 2017 and 2020.
Astia Allenzara+8 more
wiley +1 more source
Biochemical parameters of silver catfish (Rhamdia quelen) after transport with eugenol or essential oil of Lippia alba added to the water [PDF]
The transport of live fish is a routine practice in aquaculture and constitutes a considerable source of stress to the animals. The addition of anesthetic to the water used for fish transport can prevent or mitigate the deleterious effects of transport ...
A. G. Becker+50 more
core +2 more sources