Results 41 to 50 of about 584,671 (296)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Sediment transport by runoff on debris-mantled dryland hillslopes [PDF]

open access: yes, 2012
Hillslopes supply sediment to river channels, and therefore impact drainage basin functioning and evolution. The relationship between hillslope attributes and sediment flux forms the basis of geomorphic transport laws used to model the long-term ...
Martin, G.J., Michaelides, K
core   +1 more source

Climate change and human activities amplify runoff variability risks in lower reaches of large rivers

open access: yesCommunications Earth & Environment
The contributions of climate change and human activities to runoff variation have been examined in multiple individual catchments, but upstream-downstream interaction relationships remain underexplored.
Ju Gao   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Dynamics of rainfall, discharge, suspended sediment and micropollutant transport in the Moselle River, Central Europe

open access: yesEnvironmental Sciences Europe
Background Heavy rainfall causes not only high water levels and discharge but can also lead to the mobilization of sediments and pollutants to rivers. In contrast, droughts with low discharge can impair water quality due to minimized dilution.
Magdalena Uber   +4 more
doaj   +1 more source

Sensitivity and uncertainty analysis of the Variable Infiltration Capacity model in the upstream of Heihe River basin [PDF]

open access: yesProceedings of the International Association of Hydrological Sciences, 2015
The increasing water problems and eco-environmental issues of Heihe River basin have attracted widespread attention. In this research, the VIC (Variable Infiltration Capacity) model was selected to simulate the water cycle of the upstream in Heihe River ...
R. He, B. Pang
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Impact of coarse sediment supply from hillslopes to the channel in runoff-dominated, dryland fluvial systems [PDF]

open access: yes, 2014
Sediment supply from hillslopes to channels is an important control on basin functioning and evolution. However, current theoretical frameworks do not adequately consider processes of runoff-driven hillslope sediment supply, which affect river channels ...
Michaelides, Katerina   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy