Results 51 to 60 of about 607,239 (300)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Measuring and understanding biogenic influences upon cohesive sediment stability in intertidal systems [PDF]
Intertidal cohesive sediment systems are found throughout the world in areas of low hydrodynamic energy. These systems are ecologically and economically important but are under pressure from global warming, sea level rise and other anthropogenic ...
Saunders, James Edward
core +2 more sources
Use of rare earth oxides as tracers to identify sediment source areas for agricultural hillslopes [PDF]
Understanding sediment sources is essential to enable more effective targeting of in-field mitigation approaches to reduce diffuse pollution from agricultural land.
Quinton, John, Deasy, C.
core +6 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Background Heavy rainfall causes not only high water levels and discharge but can also lead to the mobilization of sediments and pollutants to rivers. In contrast, droughts with low discharge can impair water quality due to minimized dilution.
Magdalena Uber +4 more
doaj +1 more source
Deficiency and excess of groundwater iodine and their health associations
Both iodine deficiency and excess could cause thyroid disorders. By creating a national map of groundwater iodine throughout China, the authors reveal the spatial responses of diverse health risks to iodine in continental groundwater.
Ruoqi Ma +10 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Proceedings : Kansas Governor's Conference on Sediment Control [1972]
Cooperating agencies were the State Conservation Commission and the Kansas Association of Soil Conservation Districts.Descriptors: sediment control, soil erosion.Proceedings Kansas Governor's Conference On Sediment Control -- Background for Conference --
Kansas Governor's Conference on Sediment Control
core +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

