Results 71 to 80 of about 607,239 (300)

Research on the engineering practice and safety control of open-gate operation in locks

open access: yesShuili Shuiyun Gongcheng Xuebao
The open-gate operation (a mode in which the lock gate is opened to allow vessels to pass quickly and freely when the water level difference across the lock is minimal) can significantly enhance the navigation efficiency of locks.
QI Chunfeng   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Lateral sediment sources and knickzones as controls on spatio-temporal variations of sediment transport in an Alpine river [PDF]

open access: yes, 2013
Modern mixed alluvial-bedrock channels in mountainous areas provide natural laboratories for understanding the time scales at which coarse-grained material has been entrained and transported from their sources to the adjacent sedimentary sink, where ...
Norton, Kevin P.   +8 more
core   +2 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Four Decades of Reach‐Scale Declines in Total Phosphorus Across the Yellow River Basin Driven by Vegetation Restoration and Dam Impoundment

open access: yesWater Resources Research
Phosphorus (P) is a finite resource fundamental to terrestrial and aquatic productivity. However, excessive P transfer from land to rivers threatens food production and degrades water quality.
Cihong Fang   +5 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Identifying sediment sources in the tees catchment [PDF]

open access: yes, 2003
The main objective of this research is to identify the sources of suspended sediments in the River Tees. Earlier work in the Tees has focused on the extent of heavy metal concentrations in the river sediments as a result of mining m the upper catchment ...
Nelson, Tracy Jane
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Water ecological health evaluation of urban river: a case study of Zaogang River, China

open access: yesFrontiers in Ecology and Evolution
The ecological health of urban rivers serves as a critical indicator of the overall health of urban ecosystems. The water ecological health status of the Zaogang River in Changzhou City was evaluated; nine sections of the river and the Old Zaogang River ...
Jiaqi Zhang   +4 more
doaj   +1 more source

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