Results 81 to 90 of about 607,239 (300)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Hydrological factors influencing sediment concentration fluctuations in small drainage basins [PDF]
Although sediment concentrations measured in two contrasting streams in East Yorkshire fluctuate in response to similar hydrological factors, the effectiveness of these factors reflects the environmental characteristics of the drainage basins ...
Imeson, A.C.
core
Sediment transport by runoff on debris-mantled dryland hillslopes [PDF]
Hillslopes supply sediment to river channels, and therefore impact drainage basin functioning and evolution. The relationship between hillslope attributes and sediment flux forms the basis of geomorphic transport laws used to model the long-term ...
Martin, G.J., Michaelides, K
core +1 more source
Sediment-macrophyte relationships in lowland English rivers: using macrophytes for biological assessment [PDF]
PhDA study of the relationship between submerged-rooted aquatic macrophytes and the chemical and physical characteristics of sediments in lowland British rivers is described.
Clarke, Stewart Jonathon
core +2 more sources
The biotransformation of nitrate (NO3−-N), one of the main reactive nitrogen (N) types produced by human activities, is profoundly changing global climate and biodiversity.
Fei Han +7 more
doaj +1 more source
Research activities in erosion and sedimentation processes have expanded broadly during the past several years and have kept pace with generally accelerated developments in all phases of hydrology and water resources investigations.
openaire +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Sediment budget for a North Pennine upland reservoir catchment, UK [PDF]
Sediment delivery from upland fluvial systems in the UK is of considerable importance in catchment management. However, scarcity of detailed data on sediment sources, storage and linkages between geomorphic processes inhibits current understanding of ...
Holliday, Victoria Jane
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source

