Results 71 to 80 of about 1,803,074 (391)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Report and preliminary results of RV METEOR Cruise M78/3. Sediment transport off Uruguay and Argentina: from the shelf to the deep sea ; 19.05.2009 – 06.07.2009, Montevideo (Uruguay) – Montevideo (Uruguay) [PDF]

open access: yes, 2012
The waters off Uruguay and Northern Argentina offer the possibility to study sediment transport processes from ‘source-to-sink’ in a relatively small area.
Krastel, Sebastian, Wefer, Gerold
core  

A model for fluvial bedrock incision by impacting suspended and bed load sediment [PDF]

open access: yes, 2008
A mechanistic model is derived for the rate of fluvial erosion into bedrock by abrasion from uniform size particles that impact the bed during transport in both bed and suspended load.
Dietrich, William E.   +2 more
core   +1 more source

Sustainable sediment management in reservoirs and regulated rivers: Experiences from five continents

open access: yes, 2014
By trapping sediment in reservoirs, dams interrupt the continuity of sediment transport through rivers, resulting in loss of reservoir storage and reduced usable life, and depriving downstream reaches of sediments essential for channel form and aquatic ...
G. Kondolf   +18 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Evaluation of the utility of sediment data in NASQAN (National Stream Quality Accounting Network) [PDF]

open access: yes, 1983
Monthly suspended sediment discharge measurements, made by the USGS as part of the National Stream Quality Accounting Network (NASQAN), are analysed to assess the adequacy in terms of spatial coverage, temporal sampling frequency, accuracy of ...
Brooks, Norman H.   +3 more
core  

Physical and biological controls on fine sediment transport and storage in rivers [PDF]

open access: yes, 2018
Excess fine sediment, comprising particles
Casas-Mulet, R.   +10 more
core   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Extreme flood-driven fluvial bank erosion and sediment loads: direct process measurements using integrated Mobile Laser Scanning (MLS) and hydro-acoustic techniques: Direct measurement of flood-driven erosion using MLS and MBES [PDF]

open access: yes, 2016
Copyright © 2016 John Wiley & Sons, Ltd. This methods paper details the first attempt at monitoring bank erosion, flow and suspended sediment at a site during flooding on the Mekong River induced by the passage of tropical cyclones.
Aalto, Rolf   +7 more
core   +4 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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