Results 81 to 90 of about 1,722,235 (353)

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

A model for fluvial bedrock incision by impacting suspended and bed load sediment [PDF]

, 2008
A mechanistic model is derived for the rate of fluvial erosion into bedrock by abrasion from uniform size particles that impact the bed during transport in both bed and suspended load.
Dietrich, William E., Lamb, Michael P., Sklar, Leonard S.   +2 more
core   +1 more source

Deep-Water Sediment Bypass

, 2015
Submarine gravity flows are a key process for transporting large volumes of sediment from the continents to the deep sea. The location, volume, and character of the sediment bypassed by these flows dictates the areal extent and thickness of the ...
C. Stevenson, C. Jackson, D. Hodgson, S. Hubbard, J. Eggenhuisen   +4 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Numerical Modeling of Debris Flows Induced by Dam-Break Using the Smoothed Particle Hydrodynamics (SPH) Method

Applied Sciences, 2020
Dam-break flows may change into debris flows if certain conditions are satisfied, such as abundant loose material and steep slope. These debris flows are typically characterized by high density and can generate strong impact forces. Due to the complexity
Anping Shu, Shu Wang, Matteo Rubinato, Mengyao Wang, Jiping Qin, Fuyang Zhu   +5 more
doaj   +1 more source

Water induced sediment levitation enhances downslope transport on Mars [PDF]

, 2017
On Mars, locally warm surface temperatures (~293 K) occur, leading to the possibility of (transient) liquid water on the surface. However, water exposed to the martian atmosphere will boil, and the sediment transport capacity of such unstable water is ...
A Cousin, A Kereszturi, AH Treiman, AS McEwen, C Atwood-Stone, C Elachi, CJ Hansen, CM Dundas, CM Dundas, CM Dundas, CP McKay, D Reiss, D Reiss, D Reiss, DE Stillman, DE Stillman, DL Turcotte, DWG Sears, EJ Gaidos, F Costard, F Schmidt, G Jouannic, G Jouannic, HH Kieffer, J Arfstrom, J Laskar, J Raack, J Raack, J-P Bibring, JEC Scully, JF Mustard, JL Dickson, JL Heldmann, JL Heldmann, JL Heldmann, JM Goldspiel, JW Head, K Pasquon, KA Coleman, L Ojha, L Ojha, LK Fenton, M Balme, M Chojnacki, M Massé, M Vincendon, MA Kreslavsky, MC Malin, MC Malin, MG Kleinhans, MH Hecht, MI Richardson, MJ Westoby, MT Mellon, N Hoffman, N Mangold, PR Christensen, R Sullivan, RE Grimm, RM Haberle, S Diniega, S Diniega, SC Schon, SJ Conway, SJ Conway, SW Squyres, T Appéré, WV Boynton, YA Cengel   +68 more
core   +5 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Possibilities and challenges of expanding dimensions of waterway downstream of Three Gorges Dam

Water Science and Engineering, 2019
The waterway in the middle and lower reaches of the Yangtze River has long been known as the Golden Waterway and has served as an important link in the construction of the Yangtze River Economic Belt.
Tao Yan, Yun-ping Yang, Yi-bing Li, Yuan-fang Chai, Xiao-bing Cheng   +4 more
doaj  

Modelling sediment supply and transport in the River Lugg: strategies for controlling sediment loads [PDF]

, 2010
The River Lugg has particular problems with high sediment loads that have resulted in detrimental impacts on ecology and fisheries. A new dynamic, process-based model of hydrology and sediments (INCA- SED) has been developed and applied to the River Lugg
Burgess, Chris, Futter, Martyn, Lazar, Attila Nandor, Pope, Linda, Wade, Andrew John, Whitehead, Paul G, Willows, Robert   +6 more
core  

Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning

, 1991
The purpose of this review paper is to present the technical basis for establishing sediment quality criteria using equilibrium partitioning (EqP). Equilibrium partitioning is chosen because it addresses the two principal technical issues that must be ...
D. D. Toro, C. Zarba, D. Hansen, W. Berry, R. Swartz, C. Cowan, S. Pavlou, H. Allen, N. A. Thomas, P. Paquin   +9 more
semanticscholar   +1 more source