Results 81 to 90 of about 1,170,038 (344)

Bedform dimensions under supply limited conditions [PDF]

open access: yes, 2008
The volume of mobile sediment on the river bed is the primary control on the dimensions of the bed forms that develop. If an unlimited supply of sediment is available the bed form dimensions which develop are determined by the water depth, the flow ...
Ribberink, J.S., Tuijnder, A.P.
core   +1 more source

Anomalous luminescence of subglacial sediment at Haut glacier d'Arolla, Switzerland - a consequence of resetting at the glacier bed? [PDF]

open access: yes, 2010
<p>Luminescence has the potential to elucidate glacial geomorphic processes because primary glacial sediment sources and transport pathways are associated with contrasting degrees of exposure to light.
Aitken   +53 more
core   +2 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Denitrification mechanism in oxygen-rich aquatic environments through long-distance electron transfer

open access: yesnpj Clean Water, 2022
The lack of electron donors in oxygen-rich aquatic environments limits the ability of natural denitrification to remove excess nitrate, leading to eutrophication of aquatic ecosystems. Herein, we demonstrate that electron-rich substances in river or lake
Ming-Zhi Wei   +8 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Lateral Marsh Edge Erosion as a Source of Sediments for Vertical Marsh Accretion [PDF]

open access: yes, 2018
With sea level rise accelerating and sediment inputs to the coast declining worldwide, there is concern that tidal wetlands will drown. To better understand this concern, sources of sediment contributing to marsh elevation gain were computed for Plum ...
Barbier   +90 more
core   +3 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Report and preliminary results of RV METEOR Cruise M78/3. Sediment transport off Uruguay and Argentina: from the shelf to the deep sea ; 19.05.2009 – 06.07.2009, Montevideo (Uruguay) – Montevideo (Uruguay) [PDF]

open access: yes, 2012
The waters off Uruguay and Northern Argentina offer the possibility to study sediment transport processes from ‘source-to-sink’ in a relatively small area.
Krastel, Sebastian, Wefer, Gerold
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

A review of reservoir carbon Cycling: Key Processes, influencing factors and research methods

open access: yesEcological Indicators
Based on the focus on the role of reservoirs as carbon sources and sinks, this article explores their impact on the global carbon cycle. Reservoirs, which are “artificial lakes” created by human activities in rivers, are reviewed in terms of the key ...
Chunhui Li   +5 more
doaj   +1 more source

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