Results 61 to 70 of about 164,144 (307)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Total Suspended Load and Sediment Yield of Kayan River, Bulungan District, East Kalimantan

Forum Geografi, 2016
This research was carried out the the drainage system of Kayan river, Bulungan District, East Kalimantan. The purpose of the research were to study the physical conditions of the Kayan catchment area, calculate the suspended sediment load, and to define ...
Suprapto Dibyosaputro
doaj   +1 more source

Long-term in situ observations on typhoon-triggered turbidity currents in the deep sea [PDF]

, 2018
This work is supported by the National Science Foundation of China (grants 91528304, 41576005, and 41530964). We thank J. Li, X. Lyu, P. Li, K. Duan, J. Ronan, Y. Wang, P. Ma, and Y. Li for cruise assistance; G. de Lange and J.
Colin, Christophe, Kneller, Benjamin Charles, Liu, Zhifei, Wang, Meng, Zhang, Xiaodong, Zhang, Yanwei, Zhao, Shaohua, Zhao, Yulong   +7 more
core   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Sediment Modelling of a Catchment to Determine Medium-Term Erosional Trends

Land, 2023
This study was part of a project designed to simulate the long-term landform equilibrium of a rehabilitated mine site. The project utilized event Fine Suspended Sediment (FSS) fluxes in a receiving stream following a rainfall event as an indicator of ...
Devika Nair, Ken G. Evans, Sean M. Bellairs   +2 more
doaj   +1 more source

Survival of Casuarina cunninghamiana on a recovering sand-bed stream in the Wollombi Valley of coastal New South Wales [PDF]

, 2013
The successful management and restoration of riparian corridors in Australia is currently hindered by our poor understanding of the links between hydrology, fluvial geomorphology and plant population dynamics.
Chalmers, Anita, Erskine, Fiona, Erskine, Wayne   +2 more
core   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Dominant discharge in the Indus river from downstream of the Kotri Barrage dam [PDF]

Acta Scientiarum Polonorum. Formatio Circumiectus, 2014
Hydraulic data of the Indus River, downstream of Kotri Barrage dam are analyzed. An attempt has been made to determine the dominant discharge, which is defined as that discharge which over a long time period transports the most sediments and could be ...
Artur Radecki-Pawlik, Wiktoria Laszek, Karol Plesiński, Bakhshal Khan Lashari   +3 more
doaj   +1 more source

Influence of the hyporheic zone on the phosphorus dynamics of a large gravel-bed river, Garonne River, France [PDF]

, 2009
Phosphorus (P) concentrations in sediments and in surface and interstitial water from three gravel bars in a large river (Garonne River, southern France) were measured daily, downstream of a wastewater treatment plant for a city of 740 000 inhabitants ...
Ballantine, Bencala, Bencala, Bernard, Bonvallet-Garay, Bonzongo, Boulton, Brunke, Campbell, Chambers, D'Angelo, Dahm, Datta, Dorich, Dorioz, Dorioz, Edwardson, Fabre, Findlay, Findlay, Fischer, Flipo, Fox, Froelich, Gibert, Golterman, Grimm, Gunatilaka, Harms, Hendricks, Hendricks, Hieltjes, House, House, Hynes, Jarvie, Jarvie, Katsaounos, Kleeberg, Lee, Mulholland, Murdoch, Murphy, Némery, Némery, Owens, Pacini, Pelton, Psenner, Pusch, Reddy, Reddy, Rutherford, Schindler, Sharpley, Stanford, Steiger, Stone, Stone, Svendsen, Takatert, Tockner, Triska, Triska, Valett, Valett, Valett, Valett, Vervier, Vervier, Viner   +70 more
core   +2 more sources

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source