Results 121 to 130 of about 1,621,802 (299)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Understanding pool-riffle dynamics through continuous morphological simulations

open access: yes, 2011
Pool-riffle dynamics is governed by complex time and spatial interactions between water and sediment flows. In the last few decades, significant advances have been made in characterizing and modeling the hydrodynamics of pool-riffle sequences, and this ...
José F. Rodríguez   +5 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Runoff and Sediment Load Variation and Driving Factors in the Kuye River Basin

open access: yesShuitu baochi yanjiu
[Objective]The aims of this study are to investigate the spatial and temporal changes of runoff and sediment load in the Kuye River Basin, to quantify the contribution of climate change and human activities to variation of runoff and sediment load, and ...
Lan Zefan   +5 more
doaj  

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Hydrodynamic and sediment transport numerical modelling and applications at Tairua Estuary, New Zealand [PDF]

open access: yes, 2014
Tairua Estuary is a partially mixed estuary located on the east coast of the Coromandel Peninsula, North Island, New Zealand. Like many estuaries worldwide, Tairua Estuary is experiencing rapid sedimentation, which is causing a range of environmental and
Liu, Zhi
core  

The impact of mobile disarticulated shells of Cerastoderma edulis on the abrasion of a cohesive substrate

open access: yes, 2002
An annular laboratory flume was used to investigate the effect of mobile cockle shells on the erosion of a cohesive sediment bed. A standard clay bed was created and shells of differing sizes placed upon it.
Thompson, C.E.L., Amos, C.L.
core   +1 more source

Temporal sediment source tracing during storm events in the black soil region, Northeast China

open access: yesInternational Soil and Water Conservation Research
Sediment fingerprinting technology is widely used to differentiate sediment sources. However, despite its long-recognized benefits, there it has been seldom applied to assess the variability of sediment sources during storm events.
Lin Su   +4 more
doaj   +1 more source

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