Results 121 to 130 of about 1,621,802 (299)
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Understanding pool-riffle dynamics through continuous morphological simulations
Pool-riffle dynamics is governed by complex time and spatial interactions between water and sediment flows. In the last few decades, significant advances have been made in characterizing and modeling the hydrodynamics of pool-riffle sequences, and this ...
José F. Rodríguez +5 more
core +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Runoff and Sediment Load Variation and Driving Factors in the Kuye River Basin
[Objective]The aims of this study are to investigate the spatial and temporal changes of runoff and sediment load in the Kuye River Basin, to quantify the contribution of climate change and human activities to variation of runoff and sediment load, and ...
Lan Zefan +5 more
doaj
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Hydrodynamic and sediment transport numerical modelling and applications at Tairua Estuary, New Zealand [PDF]
Tairua Estuary is a partially mixed estuary located on the east coast of the Coromandel Peninsula, North Island, New Zealand. Like many estuaries worldwide, Tairua Estuary is experiencing rapid sedimentation, which is causing a range of environmental and
Liu, Zhi
core
An annular laboratory flume was used to investigate the effect of mobile cockle shells on the erosion of a cohesive sediment bed. A standard clay bed was created and shells of differing sizes placed upon it.
Thompson, C.E.L., Amos, C.L.
core +1 more source
Temporal sediment source tracing during storm events in the black soil region, Northeast China
Sediment fingerprinting technology is widely used to differentiate sediment sources. However, despite its long-recognized benefits, there it has been seldom applied to assess the variability of sediment sources during storm events.
Lin Su +4 more
doaj +1 more source

