Results 51 to 60 of about 1,505,249 (270)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
SPATIAL AND TEMPORAL DYNAMICS OF FINE FLUVIAL SEDIMENT TRANSFER: IMPLICATIONS FOR MONITORING AND MANAGEMENT OF UPLAND RIVER SYSTEMS [PDF]
, 2013 Although the impacts of changing land use on the magnitude and timing of erosion in lowland catchments are well documented, much less is known about the transfer dynamics of fine sediment through the upland hydrological networks.
PERKS, MATTHEW,THOMAS
core
A Study of the Sedimentation and Storage Capacity Depletion of a Reservoir
Slovak Journal of Civil Engineering, 2023 Theoretical and empirical equations have previously been proposed to compute the sediment trap efficiency of a reservoir. The empirical equations were developed by analyzing a limited amount of field data for reservoirs in selected areas; thus, their ...
Zerihun Yebegaeshet T.
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Post‐Wildfire Sediment Fluxes and Turbidity Plumes in a Coastal‐Draining Watershed
Earth and Space ScienceCoastal watersheds impacted by wildfires experience higher erosion resulting in increased sediment delivery to the ocean that alters limiting factors (i.e., light) for marine organisms.
Amanda M. Lopez +6 more
doaj +1 more source
River system sediment rating curve parameter estimation via integrated models
International Journal of Sediment ResearchContinuous water and sediment flow monitoring across river cross sections is essential for the management of flood- and sediment-related problems in watersheds.
Tushar Khankhoje +2 more
doaj +1 more source
Hydroclimatic control on suspended sediment dynamics of a regulated Alpine catchment: a conceptual approach [PDF]
Hydrology and Earth System Sciences, 2018 We analyse the control of hydroclimatic factors on suspended sediment concentration (SSC) in Alpine catchments by differentiating among the potential contributions of erosion and suspended sediment transport driven by erosive rainfall, defined as ...
A. Costa, D. Anghileri, P. Molnar
doaj +1 more source