Results 61 to 70 of about 18,063 (294)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A Study of the Sedimentation and Storage Capacity Depletion of a Reservoir

Slovak Journal of Civil Engineering, 2023
Theoretical and empirical equations have previously been proposed to compute the sediment trap efficiency of a reservoir. The empirical equations were developed by analyzing a limited amount of field data for reservoirs in selected areas; thus, their ...
Zerihun Yebegaeshet T.
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Post‐Wildfire Sediment Fluxes and Turbidity Plumes in a Coastal‐Draining Watershed

Earth and Space Science
Coastal watersheds impacted by wildfires experience higher erosion resulting in increased sediment delivery to the ocean that alters limiting factors (i.e., light) for marine organisms.
Amanda M. Lopez, Tesfa W. Meshesha, Christine M. Lee, Ibrahim N. Mohammed, Erin L. Hestir, Thomas C. Harmon, Dulcinea M. Avouris   +6 more
doaj   +1 more source

Magnetofossil Spike During the Paleocene-Eocene Thermal Maximum: Ferromagnetic Resonance, Rock Magnetic, and Electron Microscopy Evidence from Ancora, New Jersey, USA [PDF]

, 2007
Previous workers identified a magnetically anomalous clay layer deposited on the northern United States Atlantic Coastal Plain during the Paleocene-Eocene Thermal Maximum (PETM).
Kirschvink, Joseph L., Kopp, Robert E., Raub, Timothy D., Schumann, Dirk, Smirnov, Alexei V., Vali, Hojatollah   +5 more
core   +4 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Hydroclimatic control on suspended sediment dynamics of a regulated Alpine catchment: a conceptual approach [PDF]

Hydrology and Earth System Sciences, 2018
We analyse the control of hydroclimatic factors on suspended sediment concentration (SSC) in Alpine catchments by differentiating among the potential contributions of erosion and suspended sediment transport driven by erosive rainfall, defined as ...
A. Costa, D. Anghileri, P. Molnar
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

High-temporal resolution fluvial sediment source fingerprinting with uncertainty: a Bayesian approach [PDF]

, 2014
This contribution addresses two developing areas of sediment fingerprinting research. Specifically, how to improve the temporal resolution of source apportionment estimates whilst minimizing analytical costs and, secondly, how to consistently quantify ...
Acornley, Agency, Bilotta, Blake, Boardman, Buchanan, Collins, Collins, Collins, Collins, Cooper, D'Haen, Dutton, Egozcue, Evans, Evrard, Evrard, Fox, Gellis, Gruszowski, Hancock, Hilton, Hiscock, Hiscock, Hopkins, Horowitz, House, Huisman, Jobbágy, Kim, Krueger, Lefrançois, Legout, Lewis, Martínez-Carreras, Martínez-Carreras, Massoudieh, Matsumoto, Meteorological Office, Motha, Navratil, Olley, Owens, Palmer, Parnell, Parnell, Phillips, Plummer, Poulenard, Poulenard, Pretty, R Development Core Team, Rawlins, Rawlins, Rowan, Russell, Schindler Wildhaber, Sear, Semmens, Slimane, Small, Smith, Smith, Smith, Theuring, Thompson, Thompson, Tremblay, Walling, Walling, Wilkinson, Williams   +71 more
core   +1 more source

Suspended Sediment Rating Curves for Heterogeneous Karst Watersheds

Water Resources Research
Abstract Water‐sediment relationships are complicated in karst areas of southwest China due to regional extreme climate, special geological conditions, shallow soil layer, heterogeneous geomorphology and landscape.
Shuning Li, Xingxiu Yu, Zhenwei Li, Xianli Xu, Kelin Wang   +4 more
openaire   +1 more source