Results 71 to 80 of about 18,063 (294)

Comparison of Sediment Rating Curves Developed on Load and on Concentration [PDF]

Hydrology Research, 1997
A sediment rating curve developed as a linear regression on logged values which is back-transformed must be corrected for the bias introduced by the log transformation. This article shows that the variances are identical for linear regressions based on values of logged load and logged concentration from the same data set.
openaire   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Estimating Sediment Discharge Using Sediment Rating Curves and Artificial Neural Networks in the Shiwen River, Taiwan [PDF]

Water, 2016
Sediment in river is usually transported during extreme events related to intense rainfall and high river flows. The conventional means of collecting data in such events are risky and costly compared to water discharge measurements. Hence, the lack of sediment data has prompted the use of sediment rating curves (SRC).
Samkele Tfwala, Yu-Min Wang
openaire   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Master\u27s Project: Assessing Unpaved Road Runoff in the Mad River Watershed of Central Vermont [PDF]

, 2015
Over half of the local town roads in Vermont are unpaved (VBB, 2009). In the Mad River Watershed of central Vermont, 58% of the roads are unpaved. These compacted surfaces, despite their lack of tar, provide hundreds of miles of impermeable surfaces that
Webster, Catherine
core   +1 more source

Supraglacial forcing of subglacial drainage in the ablation zone of the Greenland ice sheet [PDF]

, 2011
Peer reviewedPublisher ...
Alley, Andrew Sole, Bartholomew, Box, Catania, Collins, Das, Douglas Mair, Fenn, Hock, Ian Bartholomew, Jemma Wadham, Kamb, McMillan, Nienow, Palmer, Parizek, Peter Nienow, Pfeffer, Pimentel, Schoof, Shepherd, Shreve, Skidmore, Steven Palmer, Sundal, Sundal, Swift, Thomas Cowton, Van de Wal, van der Veen, Zwally   +31 more
core   +4 more sources

Hydrological Foundation as a Basis for a Holistic Environmental Flow Assessment of Tropical Highland Rivers in Ethiopia [PDF]

, 2020
The sustainable development of water resources includes retaining some amount of the natural flow regime in water bodies to protect and maintain aquatic ecosystem health and the human livelihoods and wellbeing dependent upon them.
Abebe, Wubneh B., Derseh, Minychl G., McClain, Michael E., Mhiret, Demesew A., Moges, Michael M., Nigatu, Teshager A., Steenhuis, Tammo S., Tilahun, Seifu A., Van Camp, Marc, Walraevens, Kristine, Wondie, Ayalew   +10 more
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source