Results 81 to 90 of about 78,796 (264)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Quantifying sediment discharge from the Bolivian Andes into the Beni foreland basin from cosmogenic 10Be-derived denudation rates

Brazilian Journal of Geology
: Enormous volumes of sediment are produced in the Central Andes and are then delivered into the foreland basins of Amazon basin tributaries. While cosmogenic nuclides in sediment are a suitable tool to measure the denudation rates of sediment-producing ...
Hella Wittmann, Friedhelm von Blanckenburg, Jean-Loup Guyot, Laurence Maurice, Peter Kubik   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Limno-glacial deposits: Sources of sediments and processes of sedimentation

Limnology and Freshwater Biology
The article presents the theoretical postulates of limno-glacial type of sedimentation and examines its features on the example of the Onego Ice Lake.
D.A. Subetto, V.D. Strakhovenko, N.A. Belkina, A.E. Rybalko, M.S. Potakhin, Yu.A. Kublitskiy, A.V. Orlov, N.V. Kulik, N.V. Anisimov, V.I. Malov   +9 more
openaire   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Sediment source fingerprinting: benchmarking recent outputs, remaining challenges and emerging themes. [PDF]

J Soils Sediments, 2020
Collins AL, Blackwell M, Boeckx P, Chivers CA, Emelko M, Evrard O, Foster I, Gellis A, Gholami H, Granger S, Harris P, Horowitz AJ, Laceby JP, Martinez-Carreras N, Minella J, Mol L, Nosrati K, Pulley S, Silins U, da Silva YJ, Stone M, Tiecher T, Upadhayay HR, Zhang Y.   +23 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Sediment Sources and Transport Pathway Identification Based on Grain-Size Distributions on the SW Coast of Portugal

Terrestrial, Atmospheric and Oceanic Sciences, 2015
Espichel-Sines is an embayed coast in SW Portugal, consisting of two capes at both extremities, a tidal inlet and associated ebb tidal delta, a barrier spit, sandy beaches, sea cliffs, and a submarine canyon.
Xiaoqin Du, Cristina Gama, James T. Liu, and Paulo Baptista   +3 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Coupled Source-to-Sink Relationships in a Rifted Lacustrine Basin: A Case Study of the Eocene Wenchang Formation Member 6 (W6), Yangjiang East Sag, Pearl River Mouth Basin

Journal of Marine Science and Engineering
The formation and spatial distribution of sedimentary systems in rift-lake basins are jointly controlled by multiple factors, including sediment supply rates from source areas, clastic sediment transport pathways, and basin geometry and intrabasinal ...
Shangfeng Zhang, Linyuan Shi, Yaning Wang, Gaoyang Gong, Rui Han, Xinwei Qiu   +5 more
doaj   +1 more source