Results 71 to 80 of about 78,796 (264)

Unmix Optimum analysis of PAH sediment sources

Science of The Total Environment, 2019
Unmix Optimum (UnmixO) was developed to analyze data, such as sediment PAH data, that were resistant to existing methods of multivariate analysis. Using a geometrical approach, UnmixO uses multiple advanced nonlinear optimization algorithms to find potential sources that obey non-negativity constraints while optimally fitting the data.
Gary A. Norris, Ronald C. Henry
openaire   +3 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Fingerprinting using compound-specific δ13C of n-alkanes reveals the temporary role of paddy fields as a secondary source for watershed sediment loss

International Soil and Water Conservation Research
Fingerprinting generates reliable sediment provenance information which supports devising policy or practical strategies for soil conservation and sediment management, but it remains challenging in areas with fragmented landscapes and diverse land use ...
Qiang Tang, Fangxin Chen, Guangyu Zhu, Xiubin He, Jie Wei, Yusheng Zhang, Hari Ram Upadhayay, Adrian Joynes, Adrian L. Collins   +8 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Sugarcane cultivation as a major surface source of sediment in catchments from a coastal zone of Pernambuco, Brazil [PDF]

Revista Brasileira de Ciência do Solo
Identifying sediment sources is fundamental for protecting and improving soil and water quality. Conventional fingerprinting studies have often collected sediments at the overall watershed outlet only, resulting in an important spatial scale dependency ...
Rennan Cabral Nascimento, Angelo Jamil Maia, Pedro Henrique Santos de Oliveira, Ygor Jacques Agra Bezerra da Silva, Clístenes Williams Araújo do Nascimento, Tales Tiecher, Adrian Loric Collins, Yuri Jacques Agra Bezerra da Silva   +7 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Comparing the Sources of Sediment Retained by Beaver Dams and Beaver Dam Analogs

Water Resources Research
Beavers modify riverine systems by building dams that alter downstream fluxes of water and sediment. Where beavers have been lost and stream channels degraded, beaver dam analogs (BDAs) are being used to mimic the effects of beaver engineering.
Cherie J. Westbrook, David J. Cooper
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Grid‐based sediment tracing approach to determine sediment sources

Land Degradation & Development, 2019
AbstractThe diffusive and nonspecific nature of nonpoint source contaminants such as sediment makes their management and mitigation challenging. Conventional source‐based tracing techniques for sediment simply apportion downstream sediment load to diffuse upstream sources classified by a limited number of source types including underlying rock type ...
Arman Haddadchi, Murray Hicks, Jon M. Olley, Shailesh Singh, M.S. Srinivasan   +4 more
openaire   +2 more sources