Results 111 to 120 of about 91,077 (265)

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Shifted sediment-transport regimes by climate change and amplified hydrological variability in cryosphere-fed rivers. [PDF]

Sci Adv, 2023
Zhang T, Li D, Li D, East AE, Kettner AJ, Best J, Ni J, Lu X.   +7 more
europepmc   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Suspended sediment transport generated by non-hydrostatic hydrodynamics in Northern Waters of Aceh, Indonesia. [PDF]

Heliyon, 2023
Setiawan I, Haditiar Y, Syukri M, Ismail N, Rizal S.   +4 more
europepmc   +1 more source

The control of climate and base-level change on the stratigraphic architecture of fluvio-deltaic systems, investigated by quantitative analogue modelling

, 2005
River systems play an important role in the filling of sedimentary basins and record the history of external forcing processes, such as climate, tectonics and sea-level change, acting on them. They are potential reservoirs for oil, gas and water, and can
Sediment transport processes and sediment preservation, Sedimentology, van den Berg van Saparoea, A.P.H., IVAU: Instituut voor Aardwetenschappen Utrecht, Berg van Saparoea, Aart-Peter van den   +4 more
core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Evaluating the Effect of Morphologic Units on Fractional Sediment Mobility and Bedload Transport in a Small Pool‐Riffle Reach

Water Resources Research
This study examines the spatial pattern of fractional sediment mobility and assesses the influence of morphologic units on bedload transport in a small pool‐riffle reach with limited supply.
Nisreen G. Al‐Ghorani, Marwan A. Hassan, Conor McDowell   +2 more
doaj   +1 more source

Aeolian sediment transport on Io from lava-frost interactions. [PDF]

Nat Commun, 2022
McDonald GD, Méndez Harper J, Ojha L, Corlies P, Dufek J, Ewing RC, Kerber L.   +6 more
europepmc   +1 more source

A 57‐Year‐Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This report presents a case of behavioral variant frontotemporal dementia caused by mutations in the MATR3 and NOS3 genes, aiming to analyze its clinical manifestations and genetic characteristics. For a case presenting with personality changes and gait abnormalities as the initial symptoms, this study conducted a comprehensive analysis of its
Feifei Lin, Saie Huang
wiley   +1 more source

The Role of Seasonal Sediment Transport and Sintering in Shaping Titan's Landscapes: A Hypothesis. [PDF]

Geophys Res Lett, 2022
Lapôtre MGA, Malaska MJ, Cable ML.
europepmc   +1 more source