Results 111 to 120 of about 2,492,137 (249)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Assessing the Impact of Man–Made Ponds on Soil Erosion and Sediment Transport in Limnological Basins

open access: yes, 2019
The impact of ponds on basins has recently started to receive its well-deserved scientific attention. In this study, pond-induced impacts on soil erosion and sediment transport were investigated at the scale of the French Claise basin.
Chadi Abdallah   +4 more
core   +1 more source

Study on the Bedload Transport Characteristics in Mountain Rivers Under Episodic Sediment Supply Conditions

open access: yes工程科学与技术
Objective Mountain rivers are frequently subjected to short-term and episodic sediment input due to rainfall, earthquakes, bank collapses, landslides, or debris flows, causing rivers rapidly shift from a relatively stable state to a non-equilibrium ...
ZHOU Qihang   +6 more
doaj  

Transport of PFOS in aquifer sediment: Transport behavior and a distributed-sorption model. [PDF]

open access: yesSci Total Environ, 2021
Wang Y   +4 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Analysis of Changing Characteristics and Tendency of Runoff and Sediment Transport in Huangfuchuan River Watershed

open access: yesShuitu baochi yanjiu, 2009
This paper statistically analyzes the runoff and sediment transport of the Huangfuchuan river watershed in more sediment and coarse sediment region of the Yellow River,through Several non-parameter statistical methods such as the moving average check,the
WANG Xiao-jun1   +4 more
doaj  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy