Results 91 to 100 of about 325,551 (294)

Acoustic measurements of boundary layer flux profiles over a sandy rippled bed under regular waves [PDF]

, 2009
The study of boundary layer sediment transport processes requires contemporaneous measurements of the bedforms, the flow and the sediment movement. Obtaining these three parameters, at the required temporal-spatial resolutions, has been traditionally ...
Chassagne, Francois, X., Cooke, Richard, Hurther, David, Moate, Benjamin D., Thorne, Peter, D.   +4 more
core  

Development of a distributed hydrological model combined with sediment transport calculations and its application to a medium-scale basin in northeast China

Environmental Research Communications
An accurate assessment of sediment transport can assist land and resource managers in any region. The primary objective of this study was to develop a distributed hydrological model for calculating rainfall-runoff coupled with sediment transport to ...
Jinbai Huang, Qingming Wang, Shaoyuan Feng, Bin Wang, Jiawei Wen, Gengxi Zhang   +5 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Dynamic Characteristics of Suspended Load and Bed Load Transport in Meltwater Runoff of Qiyi Glacier

Shuitu Baochi Xuebao
[Objective] The transportation of sediment via glacial meltwater can not only reflect the glacial erosion and landform evolution, but also is one of the important sediment sources for the downstream river.
ZHAO Yi, WANG Ninglian, WU Songbai, ZHANG Quan, SHI Chenlie, ZHAO Mingjie   +5 more
doaj   +1 more source

Sediment transport capacity response to variations in water discharge in pressurized subglacial channels [PDF]

The Cryosphere
Sediment transport capacity in both subaerial and subglacial channels depends on the shear stress exerted across the channel bottom, which varies with water velocity and channel width.
I. Delaney, A. J. Tedstone, A. J. Tedstone, M. A. Werder, M. A. Werder, D. Farinotti, D. Farinotti   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Challenges in transferring knowledge between scales in coastal sediment dynamics

Frontiers in Marine Science, 2015
‘Packaging’ coastal sediment transport into discrete temporal and spatial scale bands is necessary for measurement programs, modelling, and design. However, determining how to best measure and parameterize information, to transfer between scales, is not ...
Shari L Gallop, Shari L Gallop, Michael eCollins, Michael eCollins, Charitha Bandula Pattiaratchi, Matthew John Eliot, Cyprien eBosserelle, Marco eGhisalberti, Lindsay Boyd Collins, Ian eEliot, Paul L.A. Erftemeijer, Piers eLarcombe, Piers eLarcombe, Ionan eMarigomez, Tanya eStul, David John White   +15 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

A NUMERICAL MODEL FOR SEDIMENT TRANSPORT

Coastal Engineering Proceedings, 1978
We introduce here a numerical two dimensional model for sediment transport which permits to compute the impact of a coastal structure on the bottom evolution. The introduction of current disturbance and some assumptions using difference of time scale between current and bottom evolutions permits to obtain a propagation equation driving the bottom ...
J.P. Lepetit, A. Hauguel
openaire   +2 more sources