Results 101 to 110 of about 2,492,137 (249)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Dynamic Characteristics of Suspended Load and Bed Load Transport in Meltwater Runoff of Qiyi Glacier

open access: yesShuitu Baochi Xuebao
[Objective] The transportation of sediment via glacial meltwater can not only reflect the glacial erosion and landform evolution, but also is one of the important sediment sources for the downstream river.
ZHAO Yi   +5 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Hydrodynamic and sediment transport numerical modelling and applications at Tairua Estuary, New Zealand [PDF]

open access: yes, 2014
Tairua Estuary is a partially mixed estuary located on the east coast of the Coromandel Peninsula, North Island, New Zealand. Like many estuaries worldwide, Tairua Estuary is experiencing rapid sedimentation, which is causing a range of environmental and
Liu, Zhi
core  

Aeolian sediment transport on Io from lava-frost interactions. [PDF]

open access: yesNat Commun, 2022
McDonald GD   +6 more
europepmc   +1 more source

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