Results 51 to 60 of about 91,077 (265)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
, 2023 This paper presents the results of experimental studies on the transport of water-sandy mixtures with the content of very fine non-cohesive fractions in steady flow.
Jarosław Biegowski +3 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Dynamics of Coarse Sediment Transfer in an Upland Bedrock River [PDF]
, 2010 Bedrock channels in UK upland environments have received relatively little attention despite their importance within upland river systems and their influence on controlling the conveyance of sediment downstream. This thesis aims to quantify and model the
CRAY, ALISTAIR,IAN
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Shui kexue jinzhan, 2019 For the Lower Yellow River,which has a major role of transferring sediment to the sea,the boundary condition has an important influence on the sediment transport efficiency.
SHEN Hongbin, WU Baosheng, WU Huali
doaj +1 more source
A Two-Dimensional Depth-Averaged Sediment Transport Mobile-Bed Model with Polygonal Meshes
, 2020 A polygonal-mesh based numerical method is developed to simulate sediment transport in mobile-bed streams with free surfaces. The flow and sediment transport governing equations are depth-averaged and solved in the two-dimensional (2D) horizontal space ...
Yong G. Lai
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Dynamics of fluvial fine sediment transfer in the River Esk, North Yorkshire, UK [PDF]
, 2006 A full understanding of the complexities of fluvial suspended sediment dynamics requires a holistic approach. The study presented here addresses fine sediment transfer in the River Esk catchment, which is suffering from the adverse effects of increased ...
Mills, Carolyn
core
Fluvial transport of suspended sediment and organic carbon during flood events in a large agricultural catchment in southwest France. [PDF]
, 2011 Water draining from a large agricultural catchment of 1 110 km2 in southwest France was sampled over an 18-month period to determine the temporal variability in suspended sediment (SS) and dissolved (DOC) and particulate organic carbon (POC) transport ...
Alexandra Coynel +12 more
core +1 more source