Results 81 to 90 of about 3,210,388 (357)

Sedimentary environmental evolution in the western bohai sea since the middle pleistocene: integrating geochemical and paleontological records

open access: yesFrontiers in Earth Science
Aiming to address under-utilized geochemical proxies in the Bohai Sea (BS) due to analytical complexity and diagenetic uncertainty, this study present a 300-kyr high-resolution geochemical and microfossils records from core DZQ01, and identified ...
Shuyu Wu   +10 more
doaj   +1 more source

Effect of sedimentary heterogeneities in the sealing formation on predictive analysis of geological CO2 storage [PDF]

open access: yes, 2019
Numerical models of geologic carbon sequestration (GCS) in saline aquifers use multiphase fluid flow-characteristic curves (relative permeability and capillary pressure) to represent the interactions of the non-wetting CO2 and the wetting brine. Relative
Alkan   +69 more
core   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Depositional Evolution and Controlling Factors of the Lower–Middle Jurassic in the Kuqa Depression, Tarim Basin, Northwest China

open access: yesApplied Sciences
The Lower–Middle Jurassic of the Kuqa Depression consists of terrestrial clastic deposits containing coal seams and thick lacustrine mudstones, and is of great significance for oil and gas exploration.
Ming Ma   +8 more
doaj   +1 more source

Ongoing transients in carbonate compensation [PDF]

open access: yes, 2010
Uptake of anthropogenic CO2 is acidifying the oceans. Over the next 2000 years, this will modify the dissolution and preservation of sedimentary carbonate.
Andreas F. Hofmann   +42 more
core   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Seasonal melting and the formation of sedimentary rocks on Mars, with predictions for the Gale Crater mound [PDF]

open access: yes, 2012
A model for the formation and distribution of sedimentary rocks on Mars is proposed. The rate-limiting step is supply of liquid water from seasonal melting of snow or ice.
Agnor   +251 more
core   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Sedimentary characteristics and evolution of the Upper Permian Wujiaping Formation in the eastern Yangtze Block

open access: yesFrontiers in Earth Science
The Upper Permian Wujiaping (WJP) Formation in the Yangtze Block (Southern China) has great potential for shale gas exploration. However, the sedimentary characteristics and environmental evolution of the WJP Formation are poorly understood. Based on 260
Yuanchong Wang   +10 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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