Results 71 to 80 of about 3,210,388 (357)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Sedimentary geology of the Middle Carboniferous of the Donbas region (Dniepr-Donets basin, Ukraine) [PDF]

, 2015
Peer reviewedPublisher ...
Abels, Hemmo A., Boekhout, Flora, Bosch, Wolter, Geluk, Mark, Hamers, Maartje, Kitchka, Alexander, Stephenson, Randell A., van der Meer, Douwe G., van Hinsbergen, Douwe J.J.   +8 more
core   +2 more sources

Middle–Late Triassic sedimentation in the Helanshan tectonic belt: Constrain on the tectono-sedimentary evolution of the Ordos Basin, North China

Geoscience Frontiers, 2019
The Helanshan tectonic belt is located to the west of the Ordos Basin, and separates the Alxa (or Yinshan) Massif to the west from the Ordos block to the east.
Jiaopeng Sun, Yunpeng Dong
semanticscholar   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Hydrocarbon-Generating Assemblages and Organic Matter Accumulation Patterns from the Basal Silurian Renheqiao Formation in Western Yunnan, China

Journal of Marine Science and Engineering
The organic-rich shales of the Upper Ordovician–Lower Silurian Renheqiao Formation in Yunnan, China, represent a valuable target for understanding marine hydrocarbon systems and offshore oil and gas exploration.
Shucan Zheng, Qinglai Feng, Xuesong Lu, Ronghe Jin, Xiaomei Nie   +4 more
doaj   +1 more source

Nonlinear Viscoelastic Compaction in Sedimentary Basins [PDF]

, 2010
In the mathematical modelling of sediment compaction and porous media flow, the rheological behaviour of sediments is typically modelled in terms of a nonlinear relationship between effective pressure $p_e$ and porosity $\phi$, that is $p_e=p_e(\phi ...
Yang, Xin-She
core   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Research progress on geogenic-contaminated high ammonium groundwater

Shuiwen dizhi gongcheng dizhi
Groundwater nitrogen contamination is one of the most prevalent water environment problems worldwide. For a long time, the high concentration of ammonium in groundwater has been attributed to inputs from various human activities.
Yao DU, Yaojin XIONG, Yamin DENG, Yanxin WANG   +3 more
doaj   +1 more source

An orbital window into the ancient Sun's mass [PDF]

, 2018
Models of the Sun's long-term evolution suggest that its luminosity was substantially reduced 2-4 billion years ago, which is inconsistent with substantial evidence for warm and wet conditions in the geological records of both ancient Earth and Mars ...
Fischer, Woodward W., Laughlin, Gregory, Spalding, Christopher   +2 more
core   +3 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source