Results 61 to 70 of about 3,210,388 (357)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Sedimentary evolution pattern influenced by sequence stratigraphy: a case study of the Nanpu Sag, Bohai Bay Basin, China

open access: yesGeoscience Letters
Identifying and characterizing sedimentary evolution patterns are crucial for assessing the distributions of source and reservoir rocks, which are fundamental to hydrocarbon exploration.
Zhongqiang Sun   +4 more
doaj   +1 more source

A four stage evolution of the White Channel gravel: Implications for stratigraphy and palaeoclimates [PDF]

open access: yes, 2014
Although the White Channel gravel (WCG) of the Klondike district, Yukon, contains gold placers which have been exploited for over a century, few sedimentological studies have been undertaken.
Chapman, Robert   +3 more
core  

Evaporites and the salinity of the ocean during the Phanerozoic: Implications for climate, ocean circulation and life [PDF]

open access: yes, 2005
A compilation of data on volumes and masses of evaporite deposits is used as the basis for reconstruction of the salinity of the ocean in the past.
Balukhovsky, A. N.   +5 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Sequence lithofacies paleogeography evolution of the Middle Permian Maokou Formation in the northwest margin of the Sichuan Basin

open access: yesFrontiers in Earth Science
Due to the present tectonic and stratigraphic distribution characteristics in the northwest margin of the Sichuan Basin are complex, which restricts the understanding of sequence lithofacies paleogeography of the Middle Permian Maokou Formation.
Wenjie Yang   +12 more
doaj   +1 more source

Seismic sedimentology of submarine fan system in the 1st Member of the Huangliu Formation, Dongfang area, Yinggehai Basin, China

open access: yes地质科技通报, 2023
Objective The Yinggehai Basin's Dongfang area is a significant area for oil and gas exploration, characterized by the presence of large-scale submarine fan complexes.
Yayun Dang
doaj   +1 more source

Lithospheric flexure and the evolution of sedimentary basins

open access: yesPhilosophical Transactions of the Royal Society of London. Series A, Mathematical and Physical Sciences, 1982
The sediments that have accumulated in sedimentary basins during geological time represent a load on the lithosphere that should respond by flexure. Simple elastic and viscoelastic (Maxwell) plate models have been used to examine quantitatively the contribution of flexure to basin formation.
Watts, A, Karner, G, Steckler, M
openaire   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Sedimentology and fluvial styles of the uppermost Cretaceous continental deposits of the Austral-Magallanes Basin, Patagonia, Argentina [PDF]

open access: yes, 2018
The sedimentary infill of the Austral-Magallanes Basin since the onset of its foreland stage in the Lago Argentino region is dominated by deep-marine and coastal deposits. However, during the Late Cretaceous the basin accumulated a thick and poorly known
Cereceda, Abril   +7 more
core   +1 more source

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