Results 51 to 60 of about 11,488 (262)

Sedimentary environmental evolution in the western bohai sea since the middle pleistocene: integrating geochemical and paleontological records

Frontiers in Earth Science
Aiming to address under-utilized geochemical proxies in the Bohai Sea (BS) due to analytical complexity and diagenetic uncertainty, this study present a 300-kyr high-resolution geochemical and microfossils records from core DZQ01, and identified ...
Shuyu Wu, Shuyu Wu, Shuyu Wu, Shuyu Wu, Hongxian Chu, Hongxian Chu, Maoguo An, Yongcai Feng, Yongcai Feng, Jun Liu, Jun Liu   +10 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Depositional Evolution and Controlling Factors of the Lower–Middle Jurassic in the Kuqa Depression, Tarim Basin, Northwest China

Applied Sciences
The Lower–Middle Jurassic of the Kuqa Depression consists of terrestrial clastic deposits containing coal seams and thick lacustrine mudstones, and is of great significance for oil and gas exploration.
Ming Ma, Changsong Lin, Yongfu Liu, Hao Li, Wenfang Yuan, Jingyan Liu, Chaoqun Shi, Manli Zhang, Fan Xu   +8 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Astronomically calibrating early Ediacaran evolution

Nature Communications
The current low-resolution chronostratigraphic framework for the early Ediacaran Period hampers a comprehensive understanding of potential trigger mechanisms for environmental upheavals and their connections to evolutionary innovation. Here, we establish
Tan Zhang, Chao Ma, Yifan Li, Chao Li, Anne-Christine Da Silva, Tailiang Fan, Qi Gao, Mingzhi Kuang, Wangwei Liu, Mingsong Li, Mingcai Hou   +10 more
doaj   +1 more source

Sedimentary Environment and Evolution of the Lower Cretaceous Jiufotang Formation in the Pijiagou and Tanjiagou Sections, Southern Fuxin Basin, NE China

Applied Sciences
The Lower Cretaceous Jiufotang Formation in the Fuxin Basin contains a proven petroleum system. However, its southern part remains underexplored due to limited drilling and fragmentary sedimentary studies.
Yiming Huang, Shichao Li, Fei Xiao, Lei Shi, Yulai Yao, Jianguo Yang   +5 more
doaj   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Magnetostratigraphy of the Late Cenozoic sediments of the West Kunlun foreland and its tectonic implications

Dizhi lixue xuebao
Objective  The West Kunlun Orogenic Belt, located on the northwestern margin of the Tibetan Plateau, is a key area for studying the tectonic uplift and expansion of the plateau.
ZHANG Lijuan, ZHANG Zhiliang, REN Zhikun, BAO Guodong, NING Yutao   +4 more
doaj   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles, Hannah F. Brubeck, Adrienne D. Tanus, Courtney N. Loecker, Punyasha Roul, Bryant R. England, Elizabeth R. Wahl, James S. Andrews, Namrata Singh, Joshua F. Baker, Patricia P. Katz, Dolores M. Shoback, Jose M. Garcia, Ariela R. Orkaby, Katherine D. Wysham   +14 more
wiley   +1 more source