Results 51 to 60 of about 636,102 (287)

Fighting Through Community Participation Based on Vegetative Conservation Approach of Wonogiri Reservoir Sedimentation in Sub - Watershed of Keduang [PDF]

open access: yes, 2012
Humans are the main trigger factors causes of sedimentation. It’s happened because of the farming and cultivation system that is not based on the principles of sustainable development. These human activities causes in damage to the environment in the
Maridi,   +3 more
core  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Bank erosion under the impacts of fluvial erosion, frost heaving/freeze-thaw process of rivers in seasonal frozen regions

open access: yesHeliyon
Bank erosion is a key feature of channel evolution in alluvial rivers, and will occur under the combined effect of hydraulic erosion and frost heave/freeze-thaw process of rivers in seasonal frozen regions. However, most research on bank erosion modeling
Jun Yang   +4 more
doaj   +1 more source

Sedimentation and subsidence history of the Lomonosov Ridge [PDF]

open access: yes, 2006
During the first scientific ocean drilling expedition to the Arctic Ocean (Arctic Coring Expedition [ACEX]; Integrated Ocean Drilling Program Expedition 302), four sites were drilled and cored atop the central part of the Lomonosov Ridge in the Arctic ...
Backman, J.   +31 more
core   +2 more sources

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

The use of sediment simulation model in determining the service life of Ekbatan Dam reservoir [PDF]

open access: yesFanāvarī-i āmūzish, 2007
Erosion and sedimentation phenomena have many destructive effects on the environment and human life. One of their most important effects is to reduce the volume of dam reservoirs.
S.A. Mir Bagheri   +2 more
doaj   +1 more source

Steady state sedimentation of ultrasoft colloids

open access: yes, 2018
The structural and dynamical properties of ultra-soft colloids - star polymers - exposed to a uniform external force field are analyzed applying the multiparticle collision dynamics approach, a hybrid coarse-grain mesoscale simulation approach, which ...
Gompper, Gerhard   +2 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The inhibitory SAPS3–AMPK interaction detected in HEK293 cells is not detectable in muscle or liver from humans or mice

open access: yesFEBS Letters, EarlyView.
This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk   +3 more
wiley   +1 more source

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