Results 71 to 80 of about 377,749 (305)
With the rapid development of the Yangtze River Basin, the issue of underwater noise pollution has become increasingly severe, which has adversely affected aquatic creatures, particularly fish.
Hongmei Zhang +5 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
(Table 5.2) Sedimentation rates of metalliferous sediments from the axial zone of the East Pacific ...
Vesselin M Dekov (6959666) +1 more
core +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
The Migration Diary of a Knickpoint in a Channelized Stream With a Cohesive Bed
This paper examines the coevolutionary roles of variable flow features and heterogeneous substrates on knickpoint migration. A conceptual model is used to depict distinct migration mechanisms in a channelized headwater system of a representative ...
A. N. (Thanos) Papanicolaou +5 more
doaj +1 more source
The role of tillage practices on soil aggregate properties has been mainly addressed at the pedon scale (i.e., soilscape scale) by treating landscape elements as disconnected.
Kenneth M. Wacha +8 more
doaj +1 more source
Solution to Secondary Sedimentation Problem by Spreadsheet and VBA [PDF]
The sedimentation process is one of the most commonly used processes in environmental engineering. Modelling and simulation of secondary sedimentation units usually requires writing mass balance equations for each layer of the settler.
Selami Demir
core
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Structure and heterogeneity of gliadin: A hydrodynamic evaluation [PDF]
A study of the heterogeneity and conformation in solution [in 70% (v/v) aq. ethanol] of gliadin proteins from wheat was undertaken based upon sedimentation velocity in the analytical ultracentrifuge, analysis of the distribution coefficients and ...
Adams, G. G. +11 more
core +1 more source

