Results 71 to 80 of about 612,434 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Confluence characteristics and regulation stage of shoals at Minjiang River mouth

Shui kexue jinzhan
Tributary-mouth channels of mountain rivers are affected by the game between the tributary and main stream, the water and sediment characteristics of which are characterized by both natural rivers and the reach affected by backwater from the main stream.
Xi HE, Ling HAO, Ya DENG, Shunchao LI, Minxiong CAO   +4 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Deep Sea Sedimentation

Environmental Health Perspectives, 1974
An important problem in the study of microparticles in the marine environment, suspended in the water column or deposited as sediment on the ocean bottom, is the determination of provenance of the microparticles-where did they come from and by what processes were they transported to the sampling location?
openaire   +2 more sources

Nitrogen removal in maturation WSP ponds via biological uptake and sedimentation of dead biomass [PDF]

, 2009
In this work a set of experiments was undertaken in a pilot-scale WSP system to determine the importance of organic nitrogen sedimentation on ammonium and total nitrogen removals in maturation ponds and its seasonal variation under British weather ...
Camargo Valero, M.A., Mara, D.D., Newton, R.J.   +2 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Sedimentation of finite-size spheres in quiescent and turbulent environments

, 2015
Sedimentation of a dispersed solid phase is widely encountered in applications and environmental flows, yet little is known about the behavior of finite-size particles in homogeneous isotropic turbulence.
Brandt, Luca, Fornari, Walter, Picano, Francesco   +2 more
core   +1 more source

Sedimentation record in the Konkan-Kerala Basin: implications for the evolution of the Western Ghats and the Western Indian passive margin [PDF]

, 2007
The Konkan and Kerala Basins constitute a major depocentre for sediment from the onshore hinterland of Western India and as such provide a valuable record of the timing and magnitude of Cenozoic denudation along the continental margin.
Allen P.A., Auden J.B., Balakrishnan T.S., Cox K.G., Drury S.A., Ghosh B.N., Gilchrist A.R., Gunnell Y., Gunnell Y., Gunnell Y., Gunnell Y., Hetenyi M., Joseph S., Kalaswad S., Kearey P., King L.C., King L.C., Krishnan M.S., Mathur R.B., McHargue T.R., Naini B.R., Nair K.M., Naqvi S.M., Ollier C.D., Ollier C.D., Pascoe E.H., Persano C., Radhakrishna B.P., Radhakrishna B.P., Raju D.S.N., Rao P.R., Rao S.V., Rao V.P., Schlich R., Singh N.K., Stephen J., Stuwe K., Summerfield M.A., Turcotte D.L., Vaidyanadhan R., Watts A.B., Widdowson M., Widdowson M., Widdowson M.   +43 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A new global gas hydrate budget based on numerical reaction-transport modeling and a novel parameterization of Holocene and Quaternary sedimentation [PDF]

, 2011
This study provides new estimates for the global methane hydrate inventory based on reaction-transport modeling [1]. A multi-1D model for POC degradation, gas hydrate formation and dissolution is presented.
Burwicz, Ewa, Rüpke, Lars, Wallmann, Klaus   +2 more
core