Results 81 to 90 of about 377,749 (305)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Confluence characteristics and regulation stage of shoals at Minjiang River mouth
Shui kexue jinzhanTributary-mouth channels of mountain rivers are affected by the game between the tributary and main stream, the water and sediment characteristics of which are characterized by both natural rivers and the reach affected by backwater from the main stream.
Xi HE +4 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Engineering Applications of Computational Fluid MechanicsDespite the widespread implementation of vegetative bioengineering, riverbank failure remains prevalent. Uncovering the hydrodynamic mechanisms governing vegetated banks is therefore imperative. To elucidate these interactions under submerged conditions,
Meng Chen +8 more
doaj +1 more source
Applied Mathematical Modelling, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Response of salinity at water source intakes to runoff and tidal dynamics of Yangtze River estuary
Shuili Shuiyun Gongcheng Xuebao, 2018 The Chenhang reservoir, Qingcaosha reservoir and Dongfengxisha reservoir are the three major water sources at the Yangtze River estuary. 80% of the Shanghai's drinking water comes from the three major water sources. The intrusion of the salt water in the
DING Lei +4 more
doaj +1 more source
Carbonate sedimentation of Site 138-854
, 2002 Carbonate sedimentation of Site 138 ...
Mayer, Larry A, Larry A Mayer (6886508)
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Study on hydrodynamic simulation and improvement scheme of urban wetlands in tidal reaches
Shuili Shuiyun Gongcheng XuebaoWetlands play crucial roles in carbon sequestration, oxygen release, and water conservation. Enhancing water exchange capacity is a key focus in wetland research. However, there is a relative scarcity of studies on wetland water regulation measures under
DING Lei +3 more
doaj +1 more source