Results 101 to 110 of about 368,619 (299)

An Estimation Method of River Dry Runoff Alteration after Upper New Reservoirs Storage

open access: yesApplied Sciences
The impact of reservoirs on downstream river hydrological characteristics is always a focal point in relevant studies exploring the relationship between rivers and dams. Anticipating river runoff patterns following the construction of new dams is crucial
Zuoqiang Chen   +5 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Sedimentation

open access: yes, 2010
Sedimentation is a classic method of biochemistry that provides first‐principle hydrodynamic and thermodynamic information about the purity, size, shape, molar mass, association energy, association stoichiometry and thermodynamic nonideality of molecules
Laue, Thomas M., Thomas Maxon Laue
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Research progress on the failure mechanism of ecological slope protection under multi-factor coupling in the Lower Yellow River

open access: yesShui kexue jinzhan
The Yellow River basin is of critical strategic importance to China's economic and social development. The lower reaches are characterized by low flow rates and high sediment concentrations,exhibiting an uncoordinated water-sediment relationship.
Dongdong JIA   +6 more
doaj   +1 more source

SEDIMENTATION OF RESERVOIRS: PREVENTION VS CLEANUP [PDF]

open access: yes
Soil erosion from cropland contributes significantly to reducing storage capacity in reservoirs. A model is developed for comparing economic desirability of various catchment level soil conservation practices. Results from an illustrative case study show
Warner, Glenn   +2 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Numerical simulation of wave overtopping at seawalls and optimization of parapet structures under coupled wind–wave effects

open access: yesShuili Shuiyun Gongcheng Xuebao
Seawalls are essential coastal engineering structures that block tidal intrusion and mitigate wave overtopping, thereby ensuring flood protection for coastal areas.
ZHU Xueqiang   +4 more
doaj   +1 more source

Global analysis of the sedimentation volume on portuguese reservoirs

open access: yes, 2014
This paper aims to examine the process of reservoir sedimentation, namely to try to estimate the sediment volume deposited in the main Portuguese reservoirs.
L. Lameiro   +4 more
core   +1 more source

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