Results 101 to 110 of about 1,948,220 (393)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Intrinsic and scattering attenuations of the Sichuan-Yunnan region in China from S coda wavesKey points

Earthquake Science
Seismic attenuation is a fundamental property of the Earth's media. Attenuation structure for the complicated geological structures with strong seismicity in the Sichuan-Yunnan region is poorly studied. In this study, we collected 108,399 waveforms of 11,
Tian Li, Lei Zhang, Xiaodong Song, Qincai Wang, Xinyu Jiang, Jinchuan Zhang, Hanlin Chen   +6 more
doaj   +1 more source

Dynamics of heavy metal accumulation in an endosulfan affected area of Kasaragod district, southwest coast of India

Radiation Protection and Environment, 2020
The heavy metal accumulation study on bed sediments of Kodangari stream situated in Enmakaje panchayath of Kasaragod district, Kerala, has been carried out. A total of 20 sediment samples along the stream were collected and analyzed for the concentration
V V Sayooj, V Vineethkumar, Sreerag Ramesh, V Prakash   +3 more
doaj   +1 more source

The signature of river- and wind-borne materials exported from Patagonia to the southern latitudes: a view from REEs and implications for paleoclimatic interpretations [PDF]

, 2004
Riverine and wind-borne materials transferred from Patagonia to the SW Atlantic exhibit a homogeneous rare earth element (REE) signature. They match well with the REE composition of Recent tephra from the Hudson volcano,and hence this implies a ...
Bidart, Susana M., Depetris, Pedro J., Gaiero, Diego M., Leleyter, Lydia, Probst, Jean-Luc   +4 more
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The Bivalve Corbicula fluminalis (Müller, 1774): an Indicator for Heavy Metals Accumulation in the Habitat of Zayandeh-Roud River [PDF]

بوم‌شناسی آبزیان, 2016
The accumulation of the heavy metals Cd, Zn, Cu, and Pb were surveyed in the samples of mantle tissues, crusts and so the habitat sediments of C. fluminalis to reveal the probable biomonitoring rule of the bivalve in the ecosystem.
Hourieh Movahedi, Mehrdad Fattollahi, Esmaeil Pir Ali, Rasoul Zamani Ahmad Mahmoudi   +3 more
doaj  

Remediation of contaminated marine sediment using bentonite, kaolin and sand as capping materials [PDF]

, 2019
There is a growing public concern over the issue of sediment contamination resulting from industrial, municipal wastewater, mining activities, and improper use of chemical fertilizer or pesticides.
Kabir Aliyu, Mohammed
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Procedure to research characteristics of finely dispersed coal bearing sludge [PDF]

, 2015
Розглянута методика досліджень властивостей тонко дисперсних осадів, що впливає на процес фільтрування. Приведені дослідження процесів, які відбуваються в порах осадів на мікрорівні.
Naumenko, V.G.
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source