Results 91 to 100 of about 159,309 (302)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The improvement of breeding methods of middle-maturing hybrids of maize in Nizhnee Povolzhye

open access: yesЗерновое хозяйство России, 2018
The article considers the results of the ecological trials (2008-2016) among the maize hybrids (FAO 200-249), developed in the different selection centers of Russia. The number of the hybrids (FAO 200-249) participating in the ecological trials was 36-43
V. I. Zhuzhukin   +3 more
doaj   +2 more sources

Organization of plant breeding in the Czech Republic after the year 1948.

open access: yesKvasný průmysl, 2006
In 1948 plant breeding and seed growing companies in the CSR were nationalized. Changes in organization of plant breeding and seed growing marked the whole period of 1948-1989.
František RŮŽIČKA
doaj   +1 more source

A magyarországi máktermelésrÅ‘l [PDF]

open access: yes
Hazánkban az utóbbi években egyre nagyobb területeken folyik alkaloida és étkezési mák termelése. Megállapítható, hogy nem igazolódtak be azok a várakozások, melyek az uniós csatlakozástól a máktermelés csökkenését várták, annak ellenére,
Karacsony, Peter   +3 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Hungary’s Biofuel Market [PDF]

open access: yes
In 2005 the Hungarian Exise Tax Act was amended regarding the sale of biofuels. The amendment stipulated that from July 1, 2007 fuels with a 4.4 volume percentage bioethanol content will be sold in Hungary. It equally stipulated that from January 1, 2008
Hingyi, Hajnalka   +2 more
core   +1 more source

Critical branching-annihilating random walk of two species

open access: yes, 2001
The effect of blocking between different species occurring in one dimension is investigated here numerically in the case of particles following branching and annihilating random walk with two offsprings.
Odor, Geza
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Experimental evaluation of organic substrates for germination testing of soybean seed [PDF]

open access: yesSelekcija i Semenarstvo, 2020
High germination of seeds and seedling establishment are critical for soybean production since it determines crop density and eventually affects the yield.
Milivojević Marija   +5 more
doaj  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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