Results 131 to 140 of about 2,153,562 (358)

Implementation of a midwifery preceptor program in Sierra Leone: a qualitative evaluation using the Consolidated Framework for Implementation Research

BMC Global and Public Health
Background Sierra Leone has the world’s third highest incidence of maternal mortality, with 443 deaths per 100,000 live births. Strengthening the country’s midwifery workforce is essential to providing adequate maternal healthcare and reducing ...
Nicholas M. Raposo, Olivia Yang, Alice Konyani, Chrisencia Owoko, Adelaide Debrah, Jennina Rose Viera, Mustapha Sonnie, Julie Mann, Brittney J. van de Water   +8 more
doaj   +1 more source

Seed development, yield and quality of two palm species growing in different tropical forest types in SE Brazil: implications for ecological restoration

, 2011
Natural forest remnants have been set as seed production fields to supply seeds of native tree species for tropical forest restoration, but the effect of different forest types on seed production has not been accessed to date for palm species.
RODRIGUES, R. R., NOVEMBRE, A. D. L. C., BRANCALION, P. H. S.   +2 more
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Tomato (Lycopersicum esculentum L.) Seed Hydrotime Analysis on Physiological and Seedling Growth Parameters in Ethiopia

Advances in Agriculture
Seed companies and farmers prioritize seeds that exhibit strong crop performances. Among the major challenges in tomato seed production are poor germinability and disease-related issues.
Yilikal Melak Assaye, Esuyawkal Demis Tenaw, Karta Kaske Kalsa   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The influence of the caruncle on the germination of castor seed under high salinity or low soil water content

, 2012
The caruncle is a structure present in the micropylar region of Euphorbiaceae seeds. This structure has the ecological function of promoting seed dispersal by ants (myrmecochory), but it is debated whether it also has an agronomical importance ...
Zanotto, Maurício Dutra, Cordoba G, O. J., Severino, L. S., Auld, D. L.   +3 more
core   +1 more source

Seed rain and soil seed banks limit native regeneration within urban forest restoration plantings in Hamilton City, New Zealand

, 2012
Restoration of native forest vegetation in urban environments may be limited due to isolation from native seed sources and to the prevalence of exotic plant species.
Overdyck, Elizabeth, Clarkson, Bruce D.
core  

Seed dormancy and germination

, 2002
Seed dormancy allows seeds to overcome periods that are unfavourable for seedling established and is therefore important for plant ecology and agriculture. Several processes are known to be involved in the induction of dormancy and in the switch from the
Leónie Bentsink, Koornneef, M., Bentsink, L., Maarten Koornneef   +3 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source