Results 141 to 150 of about 2,153,562 (358)

MicroRNA targeting specificity in mammals: determinants beyond seed pairing.

Molecules and Cells, 2007
Andrew Grimson, K. Farh, W. K. Johnston, P. Garrett-engele, Lee P. Lim, D. Bartel   +5 more
semanticscholar   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Seed Business Management in Africa

Seed industry, Seed production, Trade, Commodity markets, Marketing, Agribusiness, Crop Production/Industries, E10, E20, E21, E70, E73, F03,
MacRobert, John F.
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

The organic seed regulations framework in Europe – current status and recommendations for future development

, 2012
Organic agriculture regulations, in particular European regulation EC 889/2008, prescribe the use of organically produced seed. For many cultivated plants, however, organic seed is often not available.
Winkler, Louisa, Stubsgaard, A., Döring, T.F., Döring, Thomas F., Edith T. Lammerts van Bueren, Manfred Weinhappel, Wolfe, M S, Lammerts Van Bueren, E., Howlett, S. A., Maaike Raaijmakers, Louisa R. Winkler, Hitchings, Roger, Frederic Rey, Wilbois, Klaus-Peter, Bocci, Riccardo, Bocci, R., Pautasso, M., Wolfe, M.S., Pautasso, Marco, Raaijmakers, M., Anke Stubsgaard, Marco Pautasso, Raaijmakers, M, Wilbois, K.P., Winkler, L.R., Roger Hitchings, Howlett, S., Martin S. Wolfe, Lammerts van Bueren, E.T., Stubsgaard, Anke, Rey, F., Thomas F. Döring, Rey, F, Hitchings, R., Klaus P. Wilbois, Weinhappel, M., Riccardo Bocci, Sally Howlett   +37 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Seed trait influence on Callosobruchus maculatus behaviour and performance in legume hosts

BMC Plant Biology
Background Pulses are essential components of agricultural production systems, post-harvest losses caused by storage insect pests remain a major challenge.
Anjitha George, Bhojaraja K. Naik, K. Bhavana, Gopalareddy Krishnappa, P. Ramya, Girimalla Vanishree, Annamalai Anandan, Sanjay Kumar   +7 more
doaj   +1 more source