Results 41 to 50 of about 28,768 (256)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Variations in the Seed Coat Colour of Adzuki Beans in the Aspects of Varieties, Harvest Years and Growing Locations, using Two-Dimensional Colour Mapping

Plant Production Science, 2000
The variation in the seed coat colour of adzuki beans among varieties, harvest years and growing locations, using a two-dimensional colour mapping technique was investigated.
Jun Kato, Takashi Meguro, Masahisa M. Suzuki, Hilton C. Deeth   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Integument-Specific Transcriptional Regulation in the Mid-Stage of Flax Seed Development Influences the Release of Mucilage and the Seed Oil Content

Cells, 2021
Flax (Linum usitatissimum L.) seed oil, which accumulates in the embryo, and mucilage, which is synthesized in the seed coat, are of great economic importance for food, pharmaceutical as well as chemical industries.
Fabien Miart, Jean-Xavier Fontaine, Gaëlle Mongelard, Christopher Wattier, Michelle Lequart, Sophie Bouton, Roland Molinié, Nelly Dubrulle, Françoise Fournet, Hervé Demailly, Romain Roulard, Loïc Dupont, Arezki Boudaoud, Brigitte Thomasset, Laurent Gutierrez, Olivier Van Wuytswinkel, François Mesnard, Karine Pageau   +17 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The role of seed coat in the germination and early stages of growth of bean (Phaseolus vulgaris L.) in the presence of chickweed (Stellaria media (L.) Vill.)

Annales Universitatis Paedagogicae Cracoviensis Studia Naturae, 2019
The aim of the study was to determine the role of the seed coat in the presence of aqueous extracts from Stellaria media (L.) Vill. on germination and early growth stages of bean seeds Phaseolus vulgaris L.
Aleksandra Mazur
doaj   +1 more source

Investigation of viability rate and the effects of different breaking treatments of physical dormancy on seed germination of two tree species (Basswood and Black locust) [PDF]

علوم و فناوری بذر ایران, 2017
Basswood(Tilia begonifolia) and Blacklocust (Robinia pseudoacacia) are two forest trees with seed dormancy due to very hard seed coat. Seeds of two species were collected from Ghorogh nursery in Gorgan province to remove seed coat (breaking seed dormancy)
M. Mollashahi, A.R. Moshki, H. Ravanbakhsh   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Importance of the lignin content in the pod wall and seed coat on soybean seed physiological and health performances

Journal of Seed Science, 2023
: The effects of lignin on soybean seed quality have been studied since the early 1990s. Initially, higher lignin content in the seed coat was associated with greater resistance to mechanical damage by the seeds.
Francisco Carlos Krzyzanowski, José de Barros França-Neto, Fernando Augusto Henning   +2 more
doaj   +1 more source