Results 61 to 70 of about 35,868 (287)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Cells, 2021 Flax (Linum usitatissimum L.) seed oil, which accumulates in the embryo, and mucilage, which is synthesized in the seed coat, are of great economic importance for food, pharmaceutical as well as chemical industries.
Fabien Miart +17 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Investigation of viability rate and the effects of different breaking treatments of physical dormancy on seed germination of two tree species (Basswood and Black locust) [PDF]
علوم و فناوری بذر ایران, 2017 Basswood(Tilia begonifolia) and Blacklocust (Robinia pseudoacacia) are two forest trees with seed dormancy due to very hard seed coat. Seeds of two species were collected from Ghorogh nursery in Gorgan province to remove seed coat (breaking seed dormancy)
M. Mollashahi +2 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Optimising tetrazolium test procedures to evaluate the physiological potential of peanut seeds
, 2012 The tetrazolium test stands out as an evaluation method in determining seed physiological potential due to the diversity of the information provided. Nonetheless, efficiency depends on following appropriate procedures, which have been lacking for peanut.
Sanches, M. F. G. +4 more
core +3 more sources
Journal of Seed Science, 2023 : The effects of lignin on soybean seed quality have been studied since the early 1990s. Initially, higher lignin content in the seed coat was associated with greater resistance to mechanical damage by the seeds.
Francisco Carlos Krzyzanowski +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Expression of VINV1, SCB1 and SCS1 genes in the seed coats of contrasting soybean seeds1
Revista Ciência AgronômicaThe seed coat is vital for the proper development of soybean seeds and also, after their physiological maturity, for providing protection against various biotic and abiotic factors.
Carlos André Bahry +1 more
doaj +1 more source
Identification of genetic loci conferring seed coat color based on a high-density map in soybean
Frontiers in Plant Science, 2022 Seed coat color is a typical evolutionary trait. Identification of the genetic loci that control seed coat color during the domestication of wild soybean could clarify the genetic variations between cultivated and wild soybean.
Baoqi Yuan +11 more
doaj +1 more source