Results 81 to 90 of about 35,868 (287)

Diversity of selected Lupinus angustifolius L. genotypes at the phenotypic and DNA level with respect to microscopic seed coat structure and thickness.

open access: yesPLoS ONE, 2014
The paper investigates seed coat characteristics (as a percentage of overall seed diameter) in Lupinus angustifolius L., a potential forage crop. In the study ten L.
Jon Clements   +7 more
doaj   +1 more source

RELATIONSHIP BETWEEN SEED COAT LIGNIN CONTENT AND SEED COAT CHARACTERISTICS IN MUNG BEAN [PDF]

open access: yes, 2007
Lignin content in seed coat may have a direct effect on seed coat characteristics of mung bean genotypes (Vigna radiata). This research was designed to study the variation of seed coat lignin content among mung bean genotypes and its relationship to ...
Marwanto, Marwanto
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Cytokinin response regulator ARR16 regulates seed coat permeability in Arabidopsis natural accessions

open access: yes
International audienceThe seed coat that encases the embryo is constituted from multiple specialized-cell layers and their permeability significantly influences seed quality traits that have major agronomic impact. The regulatory mechanisms that modulate
Domergue, Frédéric   +2 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Water Uptake by Seeds in Yellow-seeded Soybean (Glycine max (L.) Merrill) Cultivars with Contrasting Imbibition Behaviors

open access: yesPlant Production Science, 2008
The rate of water uptake by seeds is assumed to be an important factor affecting the susceptibility of seeds to flooding injury, but the traits which could contribute to restricting rapid imbibition by seeds remain undetermined in yellow-seeded soybeans.
Norikazu Nakayama, Setsuko Komatsu
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Genetic inheritance of black seed coat in soybean. [PDF]

open access: yes, 2020
The standard phenotype of R gene is black hilum on black seed. The genetic control of several soybean (Glycine max L. Merr.) natural variants has not been studied. The genetic type T16 is the only occurrence with brown hilum on black seed coat.
CARPENTIERI-PIPOLO, V.
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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