Results 81 to 90 of about 2,610,066 (327)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Expression of VINV1, SCB1 and SCS1 genes in the seed coats of contrasting soybean seeds1

Revista Ciência Agronômica
The seed coat is vital for the proper development of soybean seeds and also, after their physiological maturity, for providing protection against various biotic and abiotic factors.
Carlos André Bahry, Paulo Dejalma Zimmer   +1 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Soybean Seed Coat Cracks and Green Seeds—Predisposing Conditions, Identification and Management

Seeds
Seed coat cracking and green seeds threaten soybean crop production. Seed coat cracking results from a complex interplay of genetic factors, environmental stresses, and crop management practices.
Ernane Miranda Lemes, Hugo César Rodrigues Moreira Catão   +1 more
doaj   +1 more source

THE OCCURRENCE AND SIGNIFICANCE OF MANGANESE IN THE SEED COAT OF VARIOUS SEEDS. [PDF]

Journal of the American Chemical Society, 1914
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openaire   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Fine-mapping and primary analysis of candidate genes associated with seed coat color in mung bean (Vigna radiata L.)

Journal of Integrative Agriculture
Seed coat color affects the appearance and commodity quality of mung beans (Vigna radiata L.). The substances that affect mung bean seed coat color are mainly flavonoids, which have important medicinal value.
Qian Wang, Huimin Cao, Jingcheng Wang, Zirong Gu, Qiuyun Lin, Zeyan Zhang, Xueying Zhao, Wei Gao, Huijun Zhu, Hubin Yan, Jianjun Yan, Qingting Hao, Yaowen Zhang   +12 more
doaj   +1 more source

Semipermeability of Seed Coats [PDF]

Botanical Gazette, 1913
1. The dry seed coats of Xanthium are impermeable to dry alcohol, ether, chloroform, and acetone. Becquerel'S results with the coats of other seeds are confirmed. 2. Evidence of the diffusion of oxygen through absolutely dry seed coats was not obtained. 3.
openaire   +2 more sources

Mechanisms underpinning the onset of seed coat impermeability and dormancy-break in Astragalus adsurgens

Scientific Reports, 2019
Impermeable seed coats, i.e. physical dormancy (PY) influence the germination ecology of plants from 18 angiosperm families. Astragalus adsurgens (Fabaceae; Papilinoidaae) is a perennial plant widespread in temperate regions that is thought to produce ...
G. Jaganathan, Jiajin Li, M. Biddick, Kang Han, D. Song, Yashu Yang, Ying-Ying Han, Bao-Lin Liu   +7 more
semanticscholar   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source