Results 91 to 100 of about 35,868 (287)

Isolation of nuclear proteins from flax (Linum usitatissimum L.) seed coats for gene expression regulation studies

open access: yesBMC Research Notes, 2012
Background While seed biology is well characterized and numerous studies have focused on this subject over the past years, the regulation of seed coat development and metabolism is for the most part still non-elucidated.
Renouard Sullivan   +5 more
doaj   +1 more source

Implications of seed coat cracking on soybean seed quality [PDF]

open access: yes
: Seed coat cracking is a “physiological defect” that occurs in soybean seeds, affecting their integrity. The objective of this study was to evaluate the effect of seed coat cracking on the physiological quality and storability of soybean seeds.
Geri Eduardo Meneghello   +2 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

A Legume Biofortification Quandary: Variability and genetic control of seed coat micronutrient accumulation in common beans

open access: yesFrontiers in Plant Science, 2013
Common beans (Phaseolus vulgaris L.), like many legumes, are rich in iron, zinc and certain other microelements that are generally found to be in low concentrations in cereals, other seed crops, and root or tubers and therefore are good candidates for ...
Matthew W. Blair   +3 more
doaj   +1 more source

Development of Seeding Machine for Welsh Onion Seeds without Seed Coat

open access: yesJapanese Journal of Farm Work Research, 2004
We developed a seeding machine for PaperpotTM system in which approximately 10 seeds of Welsh onion seeds without seed coat are sown in 1 hole. We examined the cell of a cell roll structure, the rotary brush and the cell roller cover, and made a prototype using the frame of a seeding machine as a basis.1) We investigated the seeding accuracy of 14 ...
KAWAMOTO, Yasunobu   +3 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Characterizing the Seed Coat in the Subtribe Angraecinae (Orchidaceae, Vandeae) and Its Taxonomic Value

open access: yes
The seeds of 121 species belonging to 38 genera of the subtribe Angraecinae (Orchidaceae) were studied in terms of their morphological characteristics under a scanning electron microscope (SEM). This study provided new data about the seed micromorphology
Roberto Gamarra   +9 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

MÉTODOS PARA SUPERAÇÃO DA DORMÊNCIA EM SEMENTES DE Garcinia gardneriana (Planch. & Triana) Zappi

open access: yesCiência Florestal, 2018
Garcinia gardneriana is a native tree species of the Atlantic Forest biome with commercial potential, industrial application, medicinal, ornamental and timber, which seeds have difficulties on germination.
Ana Patrícia Rocha   +4 more
doaj   +1 more source

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