Results 61 to 70 of about 102,099 (278)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Imbibition, germination, and early seedling growth responses of light purple and yellow seeds of red clover to distilled water, sodium chloride, and nutrient solution [PDF]

, 2019
The seeds of red clover are heteromorphic and two color morphs can be visually recognized, light purple and yellow, resulting from heterozygosity and recessive homozygosity at two loci.
Costa, A.S., Dias, A.S., Dias, L.S.
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Variation in antioxidant capacity of the seven azuki bean (Vigna angularis) varieties with different seed coat color

Plant Production Science, 2023
Azuki bean (Vigna angularis) is a small red bean commonly used in Japanese cuisine from ancient time. The most common azuki bean seed is red, but there are black, grey, brown, green, straw-colored, white, and various flecked varieties.
Norio Nagao, Yuichi Sakuma, Tatsuaki Funakoshi, Tomio Itani   +3 more
doaj   +1 more source

Allelopathic Observations in Rice (Oryza sativa L.) to Ducksalad (Heteranthera limosa) [PDF]

, 1989
More than 50 weed species infest drill-seeded rice in the U.S. and one of the most prevalent aquatic weeks is ducksalad (Heteranthera limosa). During the summer of 1988, a field experiment was conducted to identify rice accessions from the USDA/ARS rice ...
Dilday, R. H., Nastasi, Paolo, Smith, Roy J., Jr.   +2 more
core   +2 more sources

Association Studies and Legume Synteny Reveal Haplotypes Determining Seed Size in Vigna unguiculata. [PDF]

, 2013
Highly specific seed market classes for cowpea and other grain legumes exist because grain is most commonly cooked and consumed whole. Size, shape, color, and texture are critical features of these market classes and breeders target development of ...
Cisse, Ndiaga, Close, Timothy J, da Silva Vinholes, Patricia, Drabo, Issa, Ehlers, Jeffrey D, Huynh, Bao-Lam, Lucas, Mitchell R, Roberts, Philip A   +7 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Detecting shadows and low-lying objects in indoor and outdoor scenes using homographies [PDF]

, 2005
Many computer vision applications apply background suppression techniques for the detection and segmentation of moving objects in a scene. While these algorithms tend to work well in controlled conditions they often fail when applied to unconstrained ...
Beardsley, Paul, Cooke, Eddie, Kelly, Philip, O'Connor, Noel E., Smeaton, Alan F.   +4 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Seed coat color, weight and eye pattern inheritance in gamma-rays induced cowpea M2-mutant line

Journal of Genetic Engineering and Biotechnology, 2016
Gamma radiation is a very effective tool for inducing genetic variation in characters of many plants. Black seeds of M2 mutant were obtained after exposure of an Egyptian cowpea cultivar (Kaha 1) to a low dose of gamma rays.
Reda M. Gaafar, Marwa Hamouda, Abdelfattah Badr   +2 more
doaj   +1 more source