Results 51 to 60 of about 3,741 (282)
Seed coat colour is an important trait in Indian mustard. Breeding for seed coat colour needs precise knowledge of mode of inheritance and markers linked to it.
Sujata Vasudev (10742643) +8 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
The objective of this study was to evaluate seed characteristics of sponge gourd, to establish a core collection of sponge gourd with the germplasm collected throughout the Hatay region.
Kazım MAVİ +3 more
doaj +1 more source
NS-Kaća: High-protein, very early soybean cultivar [PDF]
NS-Kaća, a new, very early soybean cultivar, has been created at the Institute of Field and Vegetable Crops Novi Sad by crossing domestic and foreign genotypes. The main traits of the cultivar are its early maturity, which placed it into the 000 maturity
Vidić Miloš +3 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
This study describes the use of X-ray fluorescence spectroscopy in Crotalaria ochroleuca seed technology. This work evaluated X-ray fluorescence techniques to estimate the physiological performance of different C.
Mayara Fávero Cotrim +11 more
doaj +1 more source
Background Genome-wide association studies (GWAS) are important for the acceleration of crop improvement through knowledge of marker-trait association (MTA).
Charles U. Uba +3 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Effect of physical mutagen on expression of characters in arid legume pulse cowpea (Vigna unguiculata (L.) Walp.) [PDF]
Studies on physical induced mutagenesis, gamma rays were performed by exposing the healthy and dry seeds of cowpeavariety CO 4 to gamma rays 20, 30, 40, 50, 60 and 70 kR.
V.Ashok kumar, R.Usha kumari, N.Vairam and R.Amutha
doaj

