Results 141 to 150 of about 5,322,660 (343)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
PlantsPerennial warm-season grasses typically have reduced seed yield, making it essential to identify the critical seed yield components. An induced increase in nitrogen could help determine which components are most limiting.
Luis Leandro Chamorro +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Editorial: Weed management in organic agriculture
Frontiers in Agronomy, 2023 Silvia Fogliatto +4 more
doaj +1 more source
Achieving higher grain yield through integrated crop establishment in irrigated rice fields [PDF]
, 2006 Crop management strategies need to be improved and integrated in irrigated rice fields in order to approach yield potential, improve crop efficiency and decrease labor requirement. Crop establishment techniques (direct-seeding, nursery management, sowing
Bueno, Crisanta Sunio +4 more
core
SEEDING DENSITY OF DIFFERENT FISH SPECIES IN POLYCULTURE
Vestnik of Astrakhan State Technical University. Series: Fishing industry, 2017 The article touches upon the principles, biological basics and practical progress of introduction of specific and age polyculture of fishes. Using the results of the analysis of literary and long-term native data, there has been offered the gradation of 12 fish species from different families by resistance to habitat conditions.
openaire +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Potato yield and quality as a function of the plant density
Agricultural and Food Science, 1975 The effects of potato plant density on yield quantity and quality were investigated at the Hankkija Plant Breeding Institute from 1971-73, using seed rates of 1600, 3200 and 4800 kg/ha, and seed sizes of 40, 80 and 120 g.
Eero Varis
doaj
CENTRIFUGAL SEED SORTING AGRICULTURAL CROPS BY DENSITY [PDF]
Universum:Technical sciences, 2021 openaire +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source