Results 121 to 130 of about 3,277,284 (304)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Roles of seed and establishment limitation in determining patterns of afrotropical tree recruitment.

open access: yesPLoS ONE, 2013
Quantifying the relative importance of the multiple processes that limit recruitment may hold the key to understanding tropical tree diversity. Here we couple theoretical models with a large-scale, multi-species seed-sowing experiment to assess the ...
Connie J Clark   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The Role of Environmental Heterogeneity in the Seed Rain Pattern

open access: yesFloresta e Ambiente
We focus on understanding the influence of environmental variables on ecological processes, and such a focus promotes an integrated view of forest ecological patterns.
Monique Perini   +2 more
doaj   +1 more source

Soil seed bank dynamics in Mediterranean urban vegetation fragments [PDF]

open access: yes, 2012
Conservation of biodiversity in urban vegetation fragments is of increasingly high importance with growing urbanisation globally, particularly so in the biodiversity hotspot of the Mediterranean southwest of Western Australia.
Davis, Jessica
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Legume seed production and research in Europe [PDF]

open access: yes, 2002
Legume seed production and research in ...
Boelt, B.
core   +1 more source

Editorial: Weed management in organic agriculture

open access: yesFrontiers in Agronomy, 2023
Silvia Fogliatto   +4 more
doaj   +1 more source

Water content and GA(3)-induced embryonic cell expansion explain Euterpe edulis seed germination, rather than seed reserve mobilisation

open access: yes, 2014
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Processo FAPESP: 06/02820-1Processo FAPESP: 08/00125-0Euterpe Mulls is a key ecological species in the Atlantic forest ...
Coan, A. I.   +2 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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