Results 101 to 110 of about 74,337 (349)

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

More than symbioses : orchid ecology ; with examples from the Sydney Region [PDF]

, 2013
The Orchidaceae are one of the largest and most diverse families of flowering plants. Orchids grow as terrestrial, lithophytic, epiphytic or climbing herbs but most orchids native to the Sydney Region can be placed in one of two categories.
Entwisle, Timothy J., Perkins, Andrew J., Weston, Peter H.   +2 more
core  

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Mechanism of endocarp-imposed constraints of germination of Lannea microcarpa seeds [PDF]

, 2008
Lannea microcarpa, a multipurpose tree species from the dry African savanna, sheds seeds that often display inhibition of germination. The underlying mechanism was investigated using seeds processed from fully matured fruits collected from natural stands
Golovina, E.A., Hoekstra, F.A., Neya, O.
core   +2 more sources

Divergent Responses of Bacterial Communities to Permafrost Degradation and Their Associations With Carbon Across Vertical Profiles

Advanced Science, EarlyView.
Bacterial α‐diversity decreases, but stochasticity and community stability increase across the 15 m‐depth vertical profiles and along the degraded gradient within the active layer. The abundance and interaction of core taxa mainly control community stability in the active and permafrost layers, respectively.
Shengyun Chen, Yuzheng Gu, Ali Bahadur, Enyan Liu, Tonghua Wu, Xiaofan Zhu, Yuanqiang Zou, Hewei Liang, Peijie Wei, Linwei Wu, Qingbai Wu, Peizhi Yang, Hongyan Yu, Yunfeng Yang   +13 more
wiley   +1 more source

Dormancy of peanut seeds

Engei Gakkai zasshi, 1965
1. Small seeded varieties of Spanish and Valencia types showed only shallow dormancy just after harvest, but large seeded varieties of Virginia type showed deep dormancy continuing during rather long period.2. Differences of nature of dormancy due to difference of growing areas between Japan and Israel could hardly been observed.3.
S. NAKAMURA, T. SATO
openaire   +2 more sources

Dormancy and cardinal temperatures during seed germination of five weedy rice (Oryza spp.) strains [PDF]

, 2010
Temperature during seed imbibition has been found to influence germination rate and final percent germination. Seeds of one cultivated variety and five weedy rice strains, collected from different localities in Peninsular Malaysia, were used to ...
Adam, Puteh, Rosli, Mohamad, Roziah, Rosli   +2 more
core  

The heterotrimeric G-protein complex modulates light sensitivity in arabidopsis thaliana seed germination [PDF]

, 2009
Release of dormancy and induction of seed germination are complex traits finely regulated by hormonal signals and environmental cues such as temperature and light.
Benech-Arnold, Bewley, Borthwick, Botto, Botto, Botto, Botto, Botto, Cao, Casal, Casal, Chen, Chen, Chen, Colucci, de Lucas, Feng, Finch-Savage, Henning, Huang, Johnston, Jones, Jones, Lapik, Laserna, Mitsunori Sco, Ogawa, Oh, Oh, Oh, Pandey, Peng, Scopel, Shikha Misra, Shinomura, Trusov, Ullah, Wang, Warpeha, Yamaguchi   +39 more
core   +2 more sources