Results 61 to 70 of about 30,634 (331)
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
Promoting lentil germination and stem growth by plasma activated tap water, demineralized water and liquid fertilizer [PDF]
Tap water, demineralized water and liquid fertilizer have been activated using an atmospheric pressure plasma jet (APPJ) to investigate their benefits for the germination rate and stem elongation rate of lentils from Puy-en-Velay (France). By plasma-activating tap water, we have obtained germination rates as high as 80% (instead of 30% with tap water).
arxiv +1 more source
Objective This study analyzed longitudinal trajectories of soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and placental growth factor (PlGF) and sFlt‐1/PlGF ratio in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14‐18, 24‐26, 30‐32, 34‐36 and 38‐40 weeks), stored at ‐80°C and evaluated for ...
Nilson R. de Jesús+7 more
wiley +1 more source
Functional genomics of seed dormancy in wheat: advances and prospects
Seed dormancy is a mechanism underlying the inability of viable seeds to germinate under optimal environmental conditions. To achieve rapid and uniform germination, wheat and other cereal crops have been selected against dormancy.
Feng eGao, Belay T. Ayele
doaj +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim+3 more
wiley +1 more source
Abstract Stressful life increases the risk of mental and psychological disorders and cognitive deficits. Abscisic acid (ABA) is a plant hormone that has been recently discovered in mammalians. ABA is produced in response to stressful stimuli and it can reduce anxiety‐like behaviors and depression and improve cognitive function.
Mohammad Shabani+3 more
wiley +1 more source
A Cellular Automaton Model for Tumor Dormancy: Emergence of a Proliferative Switch [PDF]
Malignant cancers that lead to fatal outcomes for patients may remain dormant for very long periods of time. Although individual mechanisms such as cellular dormancy, angiogenic dormancy and immunosurveillance have been proposed, a comprehensive understanding of cancer dormancy and the "switch" from a dormant to a proliferative state still needs to be ...
arxiv +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
The value of internal memory for population growth in varying environments [PDF]
In varying environments it is beneficial for organisms to utilize available cues to infer the conditions they may encounter and express potentially favorable traits. However, external cues can be unreliable or too costly to use. We consider an alternative strategy where organisms exploit internal sources of information.
arxiv
Comparative Salt Tolerance Study of Some Acacia Species at Seed Germination Stage [PDF]
Objective: The purpose of this study was to assess and compare the seed germination response of six Acacia species under different NaCl concentrations in order to explore opportunities for selection and breeding salt tolerant genotypes. Methodology: Germination of seeds was evaluated under salt stresses using 5 treatment levels: 0, 100, 200, 300 and ...
arxiv +1 more source