Results 91 to 100 of about 191,044 (310)

Corynespora cassiicola in soybean seeds – incidence and transmission

Bioscience Journal, 2020
The fungus Corynespora cassiicola, causal agent of target spot in soybeans, has been considered, from the seed pathology point of view, a seed-borne pathogen of limited importance.
Augusto César Pereira Goulart, Carlos Mitinori Utiamada   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Sanitary, physiological quality and alternative treatments of Dimorphandra gardneriana Tul. seeds

Bioscience Journal, 2018
The Dimorphandra gardneriana Tul. species is widely distributed in the Brazilian territory presenting an economic and environmental importance. The aim of this study was to determine the fungi associated with Dimorphandra gardneriana seeds, assessing the
Flávio Ricardo da Silva Cruz, Rosemere dos Santos Silva, Maria das Graças Rodrigues do Nascimento, Demetrius José da Silva, Luciana Cordeiro do Nascimento   +4 more
doaj   +1 more source

Undergraduate Research Journal, Volume 15 [PDF]

, 2016
Table of Contents: The Effects of Snorkel-Based Tourism on the Behavior of Reef Fishes / by Savannah Clapp, Lauren Rowsey, and Jordan Grant (p.1-18) -- People Broken Into Pieces Trying to Join: Byzantine Erotica and the Provocative Paradox / by Kendall ...
Andrei, Anca, Clapp, Savannah, DoBoer, Kendall, Fall, Dylan, Grant, Jordan, Haley, Patrick, Holley, Jo-anne, Madhavan, Subhashini, McComb, Sofie, Noddings, Chari, Rowsey, Lauren, Usheva, Emiliya   +11 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Health and transmission of fungi associated with seeds of Luehea divaricata

Agro@mbiente On-line, 2020
Research related to the pathology of seeds of native forest species, açoita-cavalo (Luehea divaricata), is scarce. This study aimed to evaluate the sanitary and physiological quality of whipshorse seeds and the possible transmission of fungi associated ...
Alexsandra Cezimbra Quevedo, Marlove Fatima Brião Muniz, Clair Walker, Mateus Alves Saldanha   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Incidence of base rot and wilt, sanitary severity and influence about seed pathology by cultivars of common bean (Phaseolus vulgaris)

Arquivos do Instituto Biológico, 2019
: The objective of this work was to conduct a temporal evaluation of incidence of rot base and sanitary severity, and to relate the impact on the seed pathology of common bean cultivars.
Mateus Paulino Braga, Luana Machado Rezende, Lucinete Martins Barbosa Estrela, Natanael Marcos Lemes, Anderson Rodrigues Rietjens, Ana Livia Lemos Oliveira, Jakelinny Martins Silva, Laryssa Lucas Araújo Silva, Milton Luiz da Paz-Lima   +8 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Efficiency of Blotter test and agar culture medium to detect Fusarium graminearum and Pyricularia grisea in wheat seeds

Journal of Seed Science
: Seeds can be considered one of the most efficient forms to disseminate pathogens. Therefore, the use of healthy seeds is extremely important to establish a crop, and seed health testing must be performed to determine the seed sanitary quality.
Meyriele Pires de Camargo, Maria Heloisa Duarte de Moraes, José Otávio Machado Menten   +2 more
doaj   +1 more source