Results 41 to 50 of about 6,823,307 (304)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Seed ageing, survival, and the improved seed viability equation; forty years on [PDF]

open access: yes, 2022
Seed Science and Technology published ‘The quantification of ageing and survival in orthodox seeds’ four decades ago. That paper explained the improved seed viability equation, which quantifies seed longevity in response to storage environment, and the ...
Ellis, Richard H.
core   +1 more source

Biochemical and genetic analyses of Jatropha curcas L. seed composition [PDF]

open access: yes, 2011
Diminishing worldwide fossil fuel reserves coupled with the negative impact of their use on the environment has led to increased research and development of renewable energy sources.
He, Wei
core   +5 more sources

Anthocyanin content in eggplant breeding lines selected in VNISSOK under condition of hydroponic small-size cultivation

open access: yesОвощи России, 2009
Fruit color of eggplants is one of the most important traits. In the fruit peel several anthocyanins were identified. It was shown that in fruits of Japanese accessions the basic an anthocyanin was delphinidin-3-(p-coumaroyl rutinoside)-5-glucoside ...
M.I. Mamedov   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

F1-F 4 cotton hybrids obtained with introgressive cotton lines [PDF]

open access: yesE3S Web of Conferences
The article presents cytogenetic analyzes of introgressive lines obtained by intergenome crossing and F1 - F4 cotton hybrids obtained with their participation. According to the obtained results, the presence of open bivalents and univalents in MKP in the
Namazov Shadman   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Assessing the Genotypic Differences for Seed Set and Seed Abortion in Tomato Genotypes [PDF]

open access: yes, 2009
Tomato (_Lycopersicon esculentum_ Mill.) is one of the most popular fruit vegetable around the world. Seed abortion where in only a small proportion of ovules in an ovary develops into matured seeds, is a wide spread phenomenon in multi-ovulated species.
Ganeshaiah Narayana   +2 more
core  

Inheritance features and selection of actively growing Brassica rapa L. plants to be tolerant of osmotic stress

open access: yesОвощи России, 2009
Plant cultivation that should be characterized by proper yield abilities is often limited in different arable lands for the reason of abiotic and biotic stress factors.
A.N. Ignatov   +3 more
doaj   +1 more source

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