Results 81 to 90 of about 6,823,307 (304)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Овощи России, 2015 The irreciprocal self'incompatibility at site'specific hybridization of Capsicum annuum L. and its morphological features in the varieties of sweet pepper Belosnezhka and Karlik during pollination by other samples is described.
O. A. Blandinskaya +3 more
doaj +1 more source
SEED YAM PRODUCTION WITH MINITUBERS
Nigeria Agricultural Journal, 2004 The performance of various sizes of minitubers of both D. alata (UM680) and D. rotundata (Obioturugo and Abi) were evaluated for size and yield of seed yams between 1998 and 2000. Minitubers are whole but small (30-100g) tubers that farmers could simply plant directly into their farms, as is the case for seed potatoes. D.
IKEORGU, J.E.G., IGBOKWE, M.C.
openaire +3 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The Seed Industry for Dryland Crops in Eastern Kenya [PDF]
The development and promotion of improved crop varieties as well as efficient seed production, distribution, and marketing systems have contributed significantly to increased agricultural production and food security in Kenya. However, these impacts have
Njoroge, Kiarie +5 more
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Овощи России, 2015 On 2-4th of September, 2013 the International «XV EUCARPIA Meeting on Genetics and Breeding of Capsicum and Eggplant» was held in Torino (Italy). The problems of utilization of genetic resources, evaluation and release of breeding material were discussed.
T. P. Suprunova +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Seed Business Management in Africa [PDF]
Seed industry, Seed production, Trade, Commodity markets, Marketing, Agribusiness, Crop Production/Industries, E10, E20, E21, E70, E73, F03,
MacRobert, John F.
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Molecular and physiological indicators of heat tolerance in upland cotton (Gossypium hirsutum L.)
Journal of Plant InteractionsHeat stress is a major abiotic constraint limiting cotton (Gossypium hirsutum L.) productivity under climate change. This study evaluated the integrated molecular and physiological responses of fifteen upland cotton cultivars exposed to acute heat stress
Abrorjon Y. Kurbonov +7 more
doaj +1 more source
Овощи России, 2015 The resistance of the released varieties of white head cabbage to pests and diseases in the Moscow region (2006 2012 years) has been studied. The diseases and pests as well as their extension and degree of infestation of cabbage plants were recorded.
A. A. Maslova +3 more
doaj +1 more source