Results 81 to 90 of about 1,164,648 (294)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Relationship between seed harvesting method and seed physiological quality for a number of Pioneer maize hybrids [PDF]

, 2012
The seed germination and seed vigor of eight Pioneer Hi-Bred maize hybrids were evaluated immediately after harvesting and a year later. The aim was to determine whether the seed showed loss of germination and vigor when shelled mechanically.
Anda, Angéla, Berzy, Tamás, Ertsey, Katalin, Varga, Péter   +3 more
core   +1 more source

Farmers’ preferences for cotton cultivation characteristics : a discrete choice experiment in Burkina Faso [PDF]

, 2019
While a fierce debate about the advantages and disadvantages of genetically modified crops is ongoing, it is surprising that farmers are often not consulted.
Gheysen, Godelieve, Koulibaly, Bazoumana, Sanou, Edouard IR, Speelman, Stijn, Tur Cardona, Juan, Vitale, Jeffrey D   +5 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Quantitative Trait Loci for Seed Size Variation in Cucurbits – A Review

Frontiers in Plant Science, 2020
Cucurbits (Cucurbitaceae family) include many economically important fruit vegetable crops such as watermelon, pumpkin/squash, cucumber, and melon. Seed size (SS) is an important trait in cucurbits breeding, which is controlled by quantitative trait loci
Yu Guo, Yu Guo, Meiling Gao, Meiling Gao, Xiaoxue Liang, Ming Xu, Xiaosong Liu, Yanling Zhang, Xiujie Liu, Jixiu Liu, Yue Gao, Shuping Qu, Feishi Luan   +12 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Respon Pertumbuhan Dan Produksi Beberapa Varietas Kedelai Hitam (Glycine Max L.) Berdasarkan Ukuran Biji [PDF]

, 2014
The objectives of this research was to produce the large seed size of several black soybean varietiesselected based on seed size. The research was conducted on Pasar 1 Tanjung Sari, District MedanSelayang, Medan with a height of ± 25 meter above sea ...
Aulia, R. (Rizki), Bayu, E. S. (Eva), Rosmayati, R. (Rosmayati)   +2 more
core  

Measurements of accretion disc corona size in LMXB: consequences for Comptonization and LMXB models

, 2003
We present results of measurements of the radial extent of the accretion disc corona in low mass X-ray binaries. These results prove conclusively the extended nature of the ADC, with radial extent varying from 20,000 km in the faintest sources to 700,000
Abramowicz, Armitage, Barnard, Barret, Bałucińska-Church, Bałucińska-Church, Begelman, Begelman, Beloborodov, Chou, Christian, Church, Church, Church, Church, Church, Church, Church, Done, Eggleton, Fabian, Frank, Galeev, Gierliński, Haardt, Jimenez-Garate, Kluzniak, Liang, M. Bałucińska-Church, M. J. Church, Miller, Mitsuda, Morley, Narita, Narita, Nelson, Oosterbroek, Oosterbroek, Paczyński, Popham, Poutanen, Proga, Różańska, Różańska, Różańska, Shakura, Shakura, Shapiro, Sidoli, Smale, Smale, Walter, White, White, White, White, Woods, Zdziarski, Zdziarski   +58 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source