Results 81 to 90 of about 7,692,665 (255)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
How Variables Like Parent, Seed Size and Desiccation Time Affect Seed Deterioration of Quercus macrocarpa L. [PDF]
, 2009 Desiccation sensitivity is the main characteristic of recalcitrant seeds that poses limitations to practices such as storage and direct seeding. This study investigated the effect of parent tree, seed size, and desiccation time on seed variables ...
Iakovoglou, Valasia +4 more
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EFFECTS OF BIOFERTILIZER AND MACRONUTRIENTS ON THE YIELD AND YIELD COMPONENTS OF FENUGREEK SEED [PDF]
, 2022 A Thesis Submitted to the Institute of Seed Technology, Sher-e-Bangla Agricultural University, Dhaka, In Partial fulfillment of the requirements for the degree of MASTER OF SCIENCE IN SEED TECHNOLOGYThe experiment was conducted at “Central
AKTHER, MST. SADIA
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Physiological performance during storage of corn seed treated with insecticides and fungicide
Journal of Seed ScienceThe goal of storage is to maintain the characteristics that seeds have immediately after processing; however, when this is over longer periods, storage may cause loss in quality.
Cristiane Deuner +5 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Seed dormancy and germination of Vicia sativa subsp nigra and Vicia sativa subsp macrocarpa
, 2013 The objectives of this study were to determine the changes in seed dormancy for a year following harvest and to ascertain the effects of different treatments on the germination of seeds of Vicia sativa subsp. nigra and Vicia sativa subsp.
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, 2021 Seed dormancy is an adaptive response of plants to environmental changes during long-term evolution. It plays an important role in plant survival and propagation.
Zhao, Yu-Chen +4 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
APPLICATION OF PLANT GROWTH REGULATORS AND EVALUATION OF THEIR EFFECTIVENESS IN COTTON CULTIVATION
Мелиорация и гидротехникаPurpose: to analyze the application of various types of plant growth regulators and their impact on the physiological processes of cotton growth and development. Discussion.
Rita Ye. Yurkova +2 more
doaj +1 more source