Results 81 to 90 of about 13,314 (255)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

INFLUENCE OF PRODUCTION ENVIRONMENT ON SEED VIGOR [PDF]

HortScience, 1994
The environment that seeds experience during development, storage, and planting significantly affects seed vigor. Yet, relatively few studies have focused on how environment during seed development affects seed vigor. Our objective was to compare vigor of seeds developed in summer vs. winter.
openaire   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Seedling imaging analysis and traditional tests to assess okra seed vigor

Journal of Seed Science
Seed vigor testing is an important component of quality control programs adopted by seed industry. The software Seed Vigor Imaging System (SVIS) has been successfully used for seed vigor assessment in different species. The objective of this research was
Ana Lúcia Pereira Kikuti, Júlio Marcos-Filho   +1 more
doaj  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Correlation analysis between physical characteristics and seed vigor of the endangered plant Abies beshanzuensis

Xibei zhiwu xuebao
[Objective] This study aims to explore the relationship between seed morphological and physical characteristics and seed vigor of Abies beshanzuensis, in order to provide a theoretical basis for further population renewal and protection of this ...
LÜ Hongfei, LOU Chenkun, LAN Rongguang, XIONG Yanyun, YANG Yunfang, YU Mingjian   +5 more
doaj   +1 more source

New Vigor Methodology in Pearl Millet Seeds

Journal of Agricultural Science, 2019
The use of high quality seeds is of utmost importance and is intimately related to seed vigor. The objective of this study was to stablish a novel methodology for evaluating the vigor of pearl millet seeds. The experiment was performed at the Federal University of Pelotas, using 5 seed lots of pearl millet cv. BRS1501.
A. S. Suñé, D. B. Rodrigues, A. S. Almeida, C. A. Nunes, L. H. Konzen, E. Gewehr, G. A. Silveira, B. B. Reis, H. L. Chagas, L. V. M. Tunes   +9 more
openaire   +2 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Morphological and physiological traits of seeds and seedlings in two rice cultivars with contrasting early vigor

Plant Production Science, 2017
Early vigor is important for crop establishment in rice. This study was conducted to determine the seed and seedling traits in relation to early vigor in rice. Laboratory tests and pot experiments were carried out in 2013 and 2014.
Min Huang, Ruichun Zhang, Jiana Chen, Fangbo Cao, Ligeng Jiang, Yingbin Zou   +5 more
doaj   +1 more source