Results 101 to 110 of about 759,599 (310)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Genotype and environment interaction on yield and quality parameters of organically grown winter wheat – Triticum aestivum L. genotypes [PDF]

open access: yes, 2005
The interaction of genotype and environment upon yield and quality parameters of eight winter wheat (Triticum aestivum L.) genotypes was studied under organic conditions in Austria over two growing periods, 2001/2002 and 2002/2003, respectively.
Dashbaljir, Ichinkhorloo   +4 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Have Biotech Seeds Increased Maize Yields? [PDF]

open access: yes
Corn yield is determined by soils, weather, seed used and other technology choices. Global population and per capita income growth trends as well as demand from the energy sector have placed great stress on cropland use.
Hennessy, David A.   +2 more
core   +1 more source

The effect of melliferous bee (Apis mellifera carnica poll) and mechanical means on seed yield, yield components and quality of alfalfa seed (Medicago sativa L) [PDF]

open access: yesSelekcija i Semenarstvo, 2005
Number of alfalfa pollinators in free pollination was investigated as well as effect of measures that promote pollination alfalfa (using sugar syrup and mechanical means).
Jevtić Goran   +2 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Production of sainfoin seed yield [PDF]

open access: yes, 2013
This study is summing up basic technological operations significant for successful sainfoin seed production. It gives summary of: optimal swaths per each production year, meteorological condition influences during production period; optimal sowing and seed density; and recommendation for optimal seed crop fertilization.
Vučković, Savo   +5 more
openaire  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Evaluation agronomique de trois espèces de Egusi (Cucurbitaceae) utilisées dans l'alimentation au Bénin et élaboration d'un modèle de prédiction du rendement [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2006
Agronomic evaluation for three Egusi species (Cucurbitaceae) used as food in Benin and model analysis for yield prediction. Six varieties of Egusi from three species of cucurbit were evaluated for the fruit and the seed yield at the Agricultural Research
Vodouhe RS.   +5 more
doaj  

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