Results 151 to 160 of about 820,864 (392)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

BIOMASS, YIELD AND LAND EQUIVALENT RATIO OF Helianthus annus L. IN SOLE CROP AND INTERCROPPED WITH Phaseolus vulgaris L. IN HIGH VALLEYS OF MEXICO [PDF]

open access: yes, 2009
The aim of the present study was to estimate the production of biomass, yield, yield components and land equivalent ratio (LER) of sunflower 'Victoria' (Helianthus anuuss L.) in sole crop and intercropped with three cultivars of bean (Phaseolus vulgaris ...
FRANCO MORA, OMAR   +3 more
core  

Analysis of seed yield components in oilseed Brassicas [PDF]

open access: yes, 2008
Gajene vrste iz porodice Brassicaceae imaju veliki ekonomski značaj. U istraživanja su uključene dve sorte ozime uljane repice i dve sorte jare uljane repice (Brassica napus L.), dve sorte stočnog kelja (Brassica oleracea var. viridis) i dve sorte bele slačice (Sinapis alba L. subsp. alba syn. Brassica hirta). Ogled je postavljen u jesenjem i prolećnom
Marjanović-Jeromela, Ana   +4 more
openaire  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

A Comparative Analysis of the Efficacy of Three Plant Growth Regulators and Dose Optimization for Improving Agronomic Traits and Seed Yield of Purple-Flowered Alfalfa (Medicago sativa L.)

open access: yesPlants
This study evaluated the effects of different plant growth regulators and their concentration gradients on the agronomic traits, seed yield, and yield components of Medicago sativa L. cv. “Xinmu No. 5” alfalfa.
Xianwei Peng   +9 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Evaluation of Advanced Lentil Lines for Diversity in Seed Mineral Concentration, Grain Yield and Yield Components

open access: yesJournal of Agricultural Sciences, 2017
Lentil is one of the most important grain legumes, which plays a significant role in human nutrition and animal feed through the world. In developing countries, the prohibitively high cost of meat has rendered, lentil, with its high seed protein and ...
Faruk Toklu   +3 more
doaj  

Evaluation of Seed Yield and Related Components of Rapeseed Winter Cultivars Under Different Sowing dates in Karaj area [PDF]

open access: yesJournal of Agricultural Science and Sustainable Production, 2010
Sowing date is the most important factor on yield and it's components of rapeseed. Suitable sowing dates make the environmental conditions during the days of emergence and seedling establishment favorable for plant. This experiment was conducted in split
D Roodi, H Amiri-Oghan, B Alizadeh
doaj  

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